ReviewBritish journal of clinical pharmacology2014
Trials and tribulations of skin iontophoresis in therapeutics.
Review in British journal of clinical pharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03979664 (Efficacy of Dexamethasone Iontophoresis in Psoriasis), which is not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Dexamethasone Iontophoresis in Psoriasis
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Effects of Drug Administration on Postoperative Pain in Orthognathic Surgery: A Systematic Review.Clinical and experimental dental research · 2025Pooled it
- Electrotherapy modalities for rotator cuff disease.The Cochrane database of systematic reviews · 2016Pooled it
- Electrotherapy modalities for adhesive capsulitis (frozen shoulder).The Cochrane database of systematic reviews · 2014Pooled it
- Iontophoresis driven concentrations of topically administered diclofenac in skeletal muscle and blood of healthy subjects.European journal of clinical pharmacology · 2015Trial
- Advances in veterinary drug and vaccine delivery: from conventional delivery methods to innovative transdermal approaches.Drug delivery and translational research · 2026Review
- Noninvasive measurement of glucose and lactate in thermoregulatory sweat in neonates and adults.Science advances · 2026Article
- Dexamethasone Iontophoresis for Musculoskeletal Tendinopathies: A Case Series of Three Patients.Cureus · 2026Article
- Skin-Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery.Advanced healthcare materials · 2026Article
- Biocoin: an open-source wearable platform for multiplexed and multimodal biosensing.Npj biosensing · 2026Article
- Treprostinil Iontophoresis in Diabetic Foot Ulcers: A Single Ascending Dose Safety Study.Fundamental & clinical pharmacology · 2025Article
- Advances in Cell-Mediated Drug Delivery for Dermatologic Diseases: Mechanisms and Current Applications.Pharmaceutics · 2025Review
- Intelligent transdermal nanoparticles as synergizing advanced delivery systems for precision therapeutics.Materials today. Bio · 2025Review
- Pelotherapy, thalassotherapy, and electrotherapy for skin treatment: current insights and future perspectives on electropelotherapy.International journal of biometeorology · 2025Review
- Evaluation of physical and chemical modifications to drug reservoirs for stimuli-responsive microneedles.Drug delivery and translational research · 2025Article
- Iontophoresis and electroporation-assisted microneedles: advancements and therapeutic potentials in transdermal drug delivery.Drug delivery and translational research · 2025Review
- Toolkit for integrating millimeter-sized microfluidic biomedical devices with multiple membranes and electrodes.Microsystems & nanoengineering · 2025Article
- Microneedle-Mediated Treatment of Obesity.Pharmaceutics · 2025Review
- 3D-printed biopolymer-based microneedle for enhanced photodynamic therapy in melanoma treatment.Frontiers in oncology · 2025Review
- Advances in Microneedle Drug Delivery for Obesity: Mechanisms, Applications, and Perspectives.International journal of nanomedicine · 2025Review
- Advanced Wearable Devices for Monitoring Sweat Biochemical Markers in Athletic Performance: A Comprehensive Review.Biosensors · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iontophoresis is a method of non-invasive transdermal drug delivery based on the transfer of charged molecules using a low-intensity electric current. Both local and systemic administration are possible; however, the skin pharmacokinetics of iontophoretically delivered drugs is complex and difficult to anticipate. The unquestionable theoretical advantages of the technique make it attractive in several potential applications. After a brief review of the factors influencing iontophoresis, we detail the current applications of iontophoresis in therapeutics and the main potential applications under investigation, including systemic and topical drugs and focusing on the treatment of scleroderma-related ulcerations. Finally, we address the issue of safety, which could be a limitation to the routine clinical use of iontophoresis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.