ArticleBiomacromolecules2013
Free-standing polyelectrolyte membranes made of chitosan and alginate.
Article in Biomacromolecules, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 138 citations in OpenAlex.
- Programmable Physical Properties of Freestanding Chitosan Membranes Electrofabricated in Microfluidics.Membranes · 2023Article
- Chitosan-Based Biomaterials: Insights into Chemistry, Properties, Devices, and Their Biomedical Applications.Marine drugs · 2023Review
- Exploiting Polyelectrolyte Complexation for the Development of Adhesive and Bioactive Membranes Envisaging Guided Tissue Regeneration.Journal of functional biomaterials · 2022Article
- Essential Oils as Antimicrobial Active Substances in Wound Dressings.Materials (Basel, Switzerland) · 2022Article
- Green approaches for extraction, chemical modification and processing of marine polysaccharides for biomedical applications.Frontiers in bioengineering and biotechnology · 2022Review
- Biopolymer-Based Multilayer Capsules and Beads Made via Templating: Advantages, Hurdles and Perspectives.Nanomaterials (Basel, Switzerland) · 2021Review
- Polyelectrolyte Multilayer Films Based on Natural Polymers: From Fundamentals to Bio-Applications.Polymers · 2021Review
- Preparation of Hybrid Alginate-Chitosan Aerogel as Potential Carriers for Pulmonary Drug Delivery.Polymers · 2020Article
- Layer-By-Layer Assemblies of Biopolymers: Build-Up, Mechanical Stability and Molecular Dynamics.Polymers · 2020Review
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- Sequentially Moldable and Bondable Four-Dimensional Hydrogels Compatible with Cell Encapsulation.Biomacromolecules · 2018Article
- Bioinspired multilayer membranes as potential adhesive patches for skin wound healing.Biomaterials science · 2018Article
- Mussel-inspired bio-compatible free-standing adhesive films assembled layer-by-layer with water-resistance.RSC advances · 2018Article
- Cell-Adhesive Bioinspired and Catechol-Based Multilayer Freestanding Membranes for Bone Tissue Engineering.Biomimetics (Basel, Switzerland) · 2017Article
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- Control of Cell Alignment and Morphology by Redesigning ECM-Mimetic Nanotopography on Multilayer Membranes.Advanced healthcare materials · 2017Article
- Tuning cell adhesive properties via layer-by-layer assembly of chitosan and alginate.Acta biomaterialia · 2017Article
- Marine Origin Polysaccharides in Drug Delivery Systems.Marine drugs · 2016Review
- Fast and safe fabrication of a free-standing chitosan/alginate nanomembrane to promote stem cell delivery and wound healing.International journal of nanomedicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Free-standing films have increasing applications in the biomedical field as drug delivery systems for wound healing and tissue engineering. Here, we prepared free-standing membranes by the layer-by-layer assembly of chitosan and alginate, two widely used biomaterials. Our aim was to produce a thick membrane and to study the permeation of model drugs and the adhesion of muscle cells. We first defined the optimal growth conditions in terms of pH and alginate concentration. The membranes could be easily detached from polystyrene or polypropylene substrate without any postprocessing step. The dry thickness was varied over a large range from 4 to 35 μm. A 2-fold swelling was observed by confocal microscopy when they were immersed in PBS. In addition, we quantified the permeation of model drugs (fluorescent dextrans) through the free-standing membrane, which depended on the dextran molecular weight. Finally, we showed that myoblast cells exhibited a preferential adhesion on the alginate-ending membrane as compared to the chitosan-ending membrane or to the substrate side.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.