ArticleNature protocols2013
Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing.
Article in Nature protocols, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Study of Axonal Injury and Degeneration inCold Spring Harbor protocols · 2025Article
- Wallerian Degeneration and Clearance of Olfactory Receptor Neuron Axons followingCold Spring Harbor protocols · 2025Article
- Developmental and physiological impacts of pathogenic human huntingtin protein in the nervous system.Neurobiology of disease · 2024Article
- Current methods to analyze lysosome morphology, positioning, motility and function.Traffic (Copenhagen, Denmark) · 2022Review
- Detailed Imaging of Mitochondrial Transport and Precise Manipulation of Mitochondrial Function with Genetically Encoded Photosensitizers in Adult Drosophila Neurons.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Die in pieces: How Drosophila sheds light on neurite degeneration and clearance.Journal of genetics and genomics = Yi chuan xue bao · 2019Review
- Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration.Science advances · 2019Article
- In vivo imaging reveals mitophagy independence in the maintenance of axonal mitochondria during normal aging.Aging cell · 2017Article
- Methodological advances in imaging intravital axonal transport.F1000Research · 2017Review
- A simple method for imaging axonal transport in aging neurons using the adult Drosophila wing.Nature protocols · 2016Article
- Compartmentalized Regulation of Parkin-Mediated Mitochondrial Quality Control in the Drosophila Nervous System In Vivo.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Positive geotactic behaviors induced by geomagnetic field in Drosophila.Molecular brain · 2016Article
- Alcohol resistance in Drosophila is modulated by the Toll innate immune pathway.Genes, brain, and behavior · 2016Article
- Drosophila neuronal injury model allows for temporal dissection of neurodegenerative events.Neural regeneration research · 2016Article
- Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons.Journal of cell science · 2016Article
- Establishment of aJournal of biological methods · 2016Article
- Proprioceptive feedback determines visuomotor gain in Drosophila.Royal Society open science · 2016Article
- Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury.Neural regeneration research · 2015Article
- Axon injury and regeneration in the adult Drosophila.Scientific reports · 2014Article
- Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Live-imaging technology has markedly advanced in the field of neural injury and axon degeneration; however, studies are still predominantly performed in in vitro settings such as cultured neuronal cells or in model organisms such as Caenorhabditis elegans in which axons lack glial wrappings. We recently developed a new in vivo model for adult-stage neural injury in Drosophila melanogaster, using the highly accessible wing of the animal. Because the Drosophila wing is translucent and dispensable for survival, it allows clear and direct visualization of injury-induced progressive responses of axons and glia highlighted by fluorescent protein (FP) markers in live animals over time. Moreover, unlike previous Drosophila models of neural injury, this procedure does not require dissection of the CNS. Thus, the key preparation steps for in vivo imaging of the neural injury response described in this protocol can be completed within 30 min.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.