ArticleProceedings of the National Academy of Sciences of the United States of America2013
Cost-effectiveness of a community-based intervention for reducing the transmission of Schistosoma haematobium and HIV in Africa.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- A systematic review and quality appraisal of the economic evaluations of schistosomiasis interventions.PLoS neglected tropical diseases · 2022Pooled it
- Pooled it
- Integrating HIV services and other health services: A systematic review and meta-analysis.PLoS medicine · 2021Pooled it
- Economic evaluations of human schistosomiasis interventions: a systematic review and identification of associated research needs.Wellcome open research · 2020Pooled it
- Dynamic Transmission Economic Evaluation of Infectious Disease Interventions in Low- and Middle-Income Countries: A Systematic Literature Review.Health economics · 2016Pooled it
- Considering treatment of male genital schistosomiasis as a tool for future HIV prevention: a systematic review.International journal of public health · 2015Pooled it
- Correlates of prior HIV testing and schistosomiasis treatment: Baseline survey findings from the "creating demand for fishermen's schistosomiasis HIV services" (FISH) cluster-randomized trial in Mangochi, Malawi.PLoS neglected tropical diseases · 2023Trial
- Integration of female genital schistosomiasis into HIV/sexual and reproductive health and rights and neglected tropical diseases programmes and services: a scoping review.Sexual and reproductive health matters · 2023Article
- Cost-effectiveness evaluation of different control strategies for Clonorchis sinensis infection in a high endemic area of China: A modelling study.PLoS neglected tropical diseases · 2022Article
- Predicting the HIV/AIDS epidemic and measuring the effect of AIDS Conquering Project in Guangxi Zhuang Autonomous Region.PloS one · 2022Article
- Recent Advances and Methodological Considerations on Vaccine Candidates for Human Schistosomiasis.Frontiers in tropical diseases · 2021Article
- Modelling microbial infection to address global health challenges.Nature microbiology · 2019Review
- Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women.PLoS neglected tropical diseases · 2019Article
- Neglected tropical diseases and the sustainable development goals: an urgent call for action from the front line.BMJ global health · 2019Article
- Schistosomiasis is associated with incident HIV transmission and death in Zambia.PLoS neglected tropical diseases · 2018Article
- Are We on Our Way to Achieving the 2020 Goals for Schistosomiasis Morbidity Control Using Current World Health Organization Guidelines?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals.Infectious diseases of poverty · 2017Review
- Modeling infectious disease dynamics in the complex landscape of global health.Science (New York, N.Y.) · 2015Review
- Quantifying demographic and socioeconomic transitions for computational epidemiology: an open-source modeling approach applied to India.Population health metrics · 2015Article
- Impact of Schistosoma mansoni on malaria transmission in Sub-Saharan Africa.PLoS neglected tropical diseases · 2014Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
Abstract
Epidemiological studies from sub-Saharan Africa show that genital infection with Schistosoma haematobium [corrected] may increase the risk for HIV infection in young women. Therefore, preventing schistosomiasis has the potential to reduce HIV transmission in sub-Saharan Africa. We developed a transmission model of female genital schistosomiasis and HIV infections that we fit to epidemiological data of HIV and female genital schistosomiasis prevalence and coinfection in rural Zimbabwe. We used the model to evaluate the cost-effectiveness of a multifaceted community-based intervention for preventing schistosomiasis and, consequently, HIV infections in rural Zimbabwe, from the perspective of a health payer. The community-based intervention combined provision of clean water, sanitation, and health education (WSH) with administration of praziquantel to school-aged children. Considering variation in efficacy between 10% and 70% of WSH for reducing S. haematobium [corrected] transmission, our model predicted that community-based intervention is likely to be cost-effective in Zimbabwe at an aggregated WSH cost corresponding to US $725-$1,000 per individual over a 20-y intervention period. These costs compare favorably with empirical measures of WSH provision in developing countries, indicating that integrated community-based intervention for reducing the transmission of S. haematobium [corrected] is an economically attractive strategy for reducing schistosomiasis and HIV transmission in sub-Saharan Africa that would have a powerful impact on averting infections and saving lives.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.