Evidence map›Paper›PMID 23589819›Full record

ArticlePediatrics2013

Quality improvement methods increase appropriate antibiotic prescribing for childhood pneumonia.

Lilliam Ambroggio, Joanna Thomson, Eileen Murtagh Kurowski, Joshua Courter, Angela Statile, Camille Graham, Brieanne Sheehan, Srikant Iyer, Samir S Shah, Christine M White

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Management of Pediatric Pneumonia: A Decade After the Pediatric Infectious Diseases Society and Infectious Diseases Society of America Guideline.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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  8. Review
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  11. Observational
  12. Observational
  13. Article
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  18. Article
  19. Antimicrobial Stewardship in the Emergency Department.Emergency medicine clinics of North America · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lilliam AmbroggioDivision of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA. lilliam.ambroggio@cchmc.org
Joanna Thomson
Eileen Murtagh Kurowski
Joshua Courter
Angela Statile
Camille Graham
Brieanne Sheehan
Srikant Iyer
Samir S Shah
Christine M White

Funding

Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
Predicting adverse outcomes in children with community-acquired pneumoniaK01AI073729 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SHAH, SAMIR SURESH · 2008 to 2012
$674k
NCATS NIH HHS UL1 TR000077NIAID NIH HHS K01 AI073729PHS HHS NIAID K01A173729PHS HHS T32HP10027-14
6 · The paper itself

Abstract

objectiveIn August 2011, the Pediatric Infectious Disease Society and Infectious Disease Society of America published an evidence-based guideline for the management of community-acquired pneumonia (CAP) in children ≥3 months. Our objective was to evaluate if quality improvement (QI) methods could improve appropriate antibiotic prescribing in a setting without a formal antimicrobial stewardship program.

methodsAt a tertiary children's hospital, QI methods were used to rapidly implement the Pediatric Infectious Disease Society/Infectious Disease Society of America guideline recommendations for appropriate first-line antibiotic therapy in children with CAP. QI interventions focused on 4 key drivers and were tested separately in the emergency department and on the hospital medicine resident teams, using multiple plan-do-study-act cycles. Medical records of eligible patients were reviewed weekly to determine the success of prescribing recommended antibiotic therapy. The impact of these interventions on our outcome was tracked over time on run charts.

resultsAppropriate first-line antibiotic prescribing for children admitted with the diagnosis of CAP increased in the emergency department from a median baseline of 0% to 100% and on the hospital medicine resident teams from 30% to 100% within 6 months of introducing the guidelines locally at Cincinnati Children's Hospital Medical Center and has been sustained for 3 months.

conclusionsOur study demonstrates that QI methods can rapidly improve adherence to national guidelines even in settings without a formal antimicrobial stewardship program to encourage judicious antibiotic prescribing for CAP.

Indexed as

Anti-Bacterial AgentsChildChild, HospitalizedChild, PreschoolCommunity-Acquired InfectionsDrug PrescriptionsEmergency Service, HospitalFemaleGuideline AdherenceHospitals, PediatricHumansInfantLength of StayMalePneumoniaPractice Guidelines as TopicAnti-Bacterial Agentsantibiotic usepediatricpneumonia

Identifiers

PMID23589819
PMCPMC3639461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.