ArticleBlood research2013
The prevalence of vitamin D deficiency in iron-deficient and normal children under the age of 24 months.
Article in Blood research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis.Oral health & preventive dentistry · 2024Pooled it
- Iron and Bone Pathophysiology.Advances in experimental medicine and biology · 2025Review
- Article
- Association between vitamin D status and eryptosis-results from the German National Cohort Study.Annals of hematology · 2023Article
- Iron Deficiency and Iron Deficiency Anemia: Potential Risk Factors in Bone Loss.International journal of molecular sciences · 2023Review
- Article
- Vitamin D deficiency in young children with iron deficiency in Misan province, Iraq.Journal of medicine and life · 2022Article
- The Association between Standardized Serum 25-HydroxyvitaminInternational journal of clinical practice · 2022Article
- Iron and 25-hydroxyvitamin D in postmenopausal women with osteoporosis.American journal of translational research · 2022Review
- The Association Between Ferritin and Vitamin D Levels in Premenopausal Fibroid Uterus Cases With Anemia.Cureus · 2021Article
- Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh.Nutrients · 2021Article
- Sleeping without Prescription: Management of Sleep Disorders in Children with Autism with Non-Pharmacological Interventions and Over-the-Counter Treatments.Brain sciences · 2020Review
- Multiple micronutrient status and predictors of anemia in young children aged 12-23 months living in New Delhi, India.PloS one · 2019Article
- Combined deficiencies of 25-hydroxyvitamin D and anemia in preschool children with severe early childhood caries: A case-control study.Paediatrics & child health · 2018Article
- Article
- Retinol, α-tocopherol, and selected minerals in breast milk of lactating women with full-term infants in South Korea.Nutrition research and practice · 2017Article
- Vitamin D deficiency and anemia risk in children: a review of emerging evidence.Pediatric health, medicine and therapeutics · 2017Review
- Effects of Iron on Vitamin D Metabolism: A Systematic Review.International journal of preventive medicine · 2016Review
- Vitamin D and anemia: insights into an emerging association.Current opinion in endocrinology, diabetes, and obesity · 2015Review
- Observational
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIron and vitamin D deficiencies cause a variety of health issues in children, which might have long-lasting effects even in asymptomatic cases. The present study sought to elucidate the potential association between iron status and serum vitamin D levels in infants.
methodsWe evaluated 102 infants aged 3-24 months who visited the CHA Bundang Medical Center from August 2010 to July 2011. Questionnaire and laboratory data were collected. The infants were classified into iron deficiency anemia (IDA), iron deficiency (ID), and normal groups according to hemoglobin (Hb) and ferritin levels. They were then classified into vitamin D deficiency (VDD), vitamin D insufficiency (VDI), and vitamin D sufficiency (VDS) groups according to 25-hydroxyvitamin D [25(OH)D] levels.
resultsVDD was present in 67% of IDA, 53% of ID, and 29% of normal subjects. The proportion of breastfed infants was the highest in the IDA (97%) and VDD (96%) groups. The odds ratio for the likelihood of iron-deficient infants to have subnormal vitamin D levels was 4.115. There was a significant correlation between Hb and 25(OH)D levels. Plasma 25(OH)D levels were lower in the winter/spring. Body mass index values were higher in the IDA/ID groups. Iron, age, and season were predictors of 25(OH)D levels.
conclusionThe prevalence of iron and vitamin D deficiency was high in breastfed infants. There was also a significant association between Hb and 25(OH)D levels in infants. Since all breastfed infants should receive vitamin D supplementation, there should also be concern about concurrent deficiencies in infants with IDA.
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