Evidence map›Paper›PMID 23589767›Full record

ArticleJournal of materials chemistry. B2013

Tobacco mosaic virus rods and spheres as supramolecular high-relaxivity MRI contrast agents.

Michael A Bruckman, Stephen Hern, Kai Jiang, Chris A Flask, Xin Yu, Nicole F Steinmetz

Open access · greenAbstract read
In one paragraph

Article in Journal of materials chemistry. B, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 98 citations in OpenAlex.

  1. Review
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  5. TheBiomaterials science · 2021
    Article
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  11. Plant Virus Nanoparticles for Anti-cancer Therapy.Frontiers in bioengineering and biotechnology · 2021
    Review
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  17. Physical, chemical, and synthetic virology: Reprogramming viruses as controllable nanodevices.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Michael A BruckmanDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH 44106, USA.
Stephen Hern
Kai Jiang
Chris A Flask
Xin Yu
Nicole F Steinmetz
Case Western Reserve University · USUniversity School · US

Funding

Phenotypic characterization of nitric oxide regulation of cardiac function by MRIR01HL073315 · NHLBI · WASHINGTON UNIVERSITY · PI YU, XIN · 2004 to 2014
$3.4M
NEW FACULTY RECRUITMENT IMAGE-GUIDED CANCER THERAPEUTICSP30EB011317 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DUERK, JEFFREY L. · 2009 to 2010
$762k
NHLBI NIH HHS R01 HL073315NIBIB NIH HHS P30 EB011317
6 · The paper itself

Abstract

To compensate for the low sensitivity of magnetic resonance imaging (MRI), nanoparticles have been developed to deliver high payloads of contrast agents to sites of disease. Here, we report the development of supramolecular MRI contrast agents using the plant viral nanoparticle tobacco mosaic virus (TMV). Rod-shaped TMV nanoparticles measuring 300×18 nm were loaded with up to 3,500 or 2,000 chelated paramagnetic gadolinium (III) ions selectively at the interior (iGd-TMV) or exterior (eGd-TMV) surface, respectively. Spatial control is achieved through targeting either tyrosine or carboxylic acid side chains on the solvent exposed exterior or interior TMV surface. The ionic T

Indexed as

contrast agentmagnetic resonance imagingtobacco mosaic virusviral nanoparticle

Identifiers

PMID23589767
PMCPMC3624747
OpenAlexW2069599385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.