Evidence map›Paper›PMID 23588813›Full record

ReviewWorld journal of urology2014

The role of functional imaging in the era of targeted therapy of renal cell carcinoma.

Margarita Braunagel, Anno Graser, Maximilian Reiser, Mike Notohamiprodjo

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Active surveillance of small renal masses.Insights into imaging · 2020
    Review
  4. Article
  5. Imaging features of solid renal masses.The British journal of radiology · 2017
    Review
  6. Article
  7. Alternate Metabolic Programs Define Regional Variation of Relevant Biological Features in Renal Cell Carcinoma Progression.Clinical cancer research : an official journal of the American Association for Cancer Research · 2016
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Margarita BraunagelDepartment of Clinical Radiology, University Hospitals Munich, Campus Grosshadern, Marchioninistrasse 15, 81377, Munich, Germany, Margarita.Braunagel@med.uni-muenchen.de.
Anno Graser
Maximilian Reiser
Mike Notohamiprodjo
München Klinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiangiogenic therapies interacting with tumor-specific pathways have been established for targeted therapy of renal cell carcinoma (RCC). However, evaluation of tumor response based on morphologic tumor diameter measurements has limitations, as tumor shrinkage may lag behind pathophysiological response. Functional imaging techniques such as dynamic contrast-enhanced (DCE) ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI), unenhanced diffusion-weighted MRI (DW-MRI), and also metabolic imaging with positron emission tomography (PET) have the ability to assess physiological parameters and to predict and monitor therapy response. Assessment of changes in vascularity, cellularity, oxygenation, and glucose uptake with functional imaging during targeted therapy may correlate with progression-free survival and can predict tumor response or progression. In this review, we explore the potential of functional imaging techniques for assessing the effects of targeted therapy of RCC and as well review the reproducibility and limitations.

Indexed as

Molecular Targeted TherapyAntineoplastic AgentsCarcinoma, Renal CellDiagnostic ImagingHumansKidney NeoplasmsMagnetic Resonance ImagingOrgan SizePositron-Emission TomographyTomography, X-Ray ComputedTreatment OutcomeUltrasonographyAntineoplastic Agents

Identifiers

PMID23588813
OpenAlexW2038789306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.