Evidence map›Paper›PMID 23588257›Full record

Trial reportEuropean journal of applied physiology2013

Effects of isometric handgrip training dose on resting blood pressure and resistance vessel endothelial function in normotensive women.

Mark B Badrov, Cassandra L Bartol, Matthew A DiBartolomeo, Philip J Millar, Nancy H McNevin, Cheri L McGowan

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02844296 (Efficacy of a Short-bout Handgrip Exercise Intervention for Smoking Cessation), which is not on this map. Cited by 45 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 8 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02844296 nacompletednot on this mapstarted 2016, after this paper: background citation

Efficacy of a Short-bout Handgrip Exercise Intervention for Smoking Cessation: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2016 to 2018Enrolled208ConditionsSmoking CessationArmsVideo about exercise, App about exercise, Leaflet about exercise, Video about diet, App about diet
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 8 syntheses or guidelines pooled it, 100 citations in OpenAlex.

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  7. Isometric exercise training for blood pressure management: a systematic review and meta-analysis to optimize benefit.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mark B BadrovPhysical Activity and Cardiovascular Research Laboratory, Department of Kinesiology, University of Windsor, 401 Sunset Avenue, Windsor, ON, N9B 3P4, Canada. badrovm@uwindsor.ca
Cassandra L Bartol
Matthew A DiBartolomeo
Philip J Millar
Nancy H McNevin
Cheri L McGowan
University of Windsor · CAToronto General Hospital · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Isometric handgrip (IHG) training lowers resting blood pressure (BP) in both hypertensives and normotensives, yet the effect of training dose on the magnitude of reduction and the mechanisms associated with the hypotensive response are elusive. We investigated, in normotensive women, the effects of two different doses of IHG training on resting BP, and explored improved resistance vessel endothelial function and heart rate variability (HRV) as potential mechanisms of BP reduction. Resting BP, HRV, and resistance vessel endothelial function (venous strain-gauge plethysmography with reactive hyperemia) were assessed in 32 women before and after 4 and 8 weeks of 3×/week (n = 12) or 5×/week (n = 11) IHG training (four, 2-min unilateral contractions at 30 % maximal voluntary contraction), or 0×/week control (n = 9). IHG training decreased systolic BP in the 3×/week (94 ± 6 to 91 ± 6 to 88 ± 5 mmHg, pre- to mid- to post-training; P < 0.01) and 5×/week (97 ± 11 to 90 ± 9 to 91 ± 9 mmHg, P < 0.01) groups, concomitant with increased forearm reactive hyperemic blood flow (26 ± 7 to 30 ± 8 to 36 ± 9 mL/min/100 mL tissue, P < 0.01; and 26 ± 7 to 29 ± 7 to 38 ± 13 mL/min/100 mL tissue, P < 0.01, respectively), yet both remained unchanged in the control group. No changes were observed in diastolic BP, mean arterial BP, or any indices of HRV in any group (all P > 0.05). In conclusion, IHG training lowers resting systolic BP and improves resistance vessel endothelial function independent of training dose in normotensive women.

Indexed as

Blood PressureExerciseHand StrengthIsometric ContractionAdultEndothelium, VascularFemaleForearmHumans

Identifiers

PMID23588257
OpenAlexW2027469795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.