Evidence map›Paper›PMID 23587435›Full record

Trial reportThe Journal of pediatrics2013

Effect of nutritional rehabilitation on gastric motility and somatization in adolescents with anorexia.

Maria E Perez, Brian Coley, Wallace Crandall, Carlo Di Lorenzo, Terrill Bravender

Abstract readClinical Trial
In one paragraph

Trial report in The Journal of pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Evaluating disorders of gut-brain interaction in eating disorders.The International journal of eating disorders · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Altered Insula Activity during Visceral Interoception in Weight-Restored Patients with Anorexia Nervosa.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria E PerezDivision of Pediatric Gastroenterology, Nationwide Children's Hospital, Columbus, OH, USA. maria.perez@atlantichealth.org.
Brian Coley
Wallace Crandall
Carlo Di Lorenzo
Terrill Bravender
Nationwide Children's Hospital · USCincinnati Children's Hospital Medical Center · US

Funding

The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
NCATS NIH HHS UL1 TR000090
6 · The paper itself

Abstract

objectiveTo examine gastric function, as well as the presence of somatic complaints, anxiety symptoms, and functional gastrointestinal disorders (FGIDs), in adolescents with anorexia nervosa (AN) before and after nutritional rehabilitation. STUDY

designSixteen females with AN and 22 healthy controls with similar demographic profiles were included. Gastric emptying (measured as residual gastric volume) and gastric accommodation (measured as postprandial antral diameter) were assessed with abdominal ultrasonography. Participants completed the Children's Somatization Inventory (CSI), the Screen for Child Anxiety-Related Emotional Disorders, and the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III version. All testing was repeated 3-4 months later.

resultsBody mass index in the AN group improved over time (P = .012). Fasting gastric parameters were similar in the 2 groups. Maximum postprandial antral diameter was significantly greater in controls compared with the AN group (P = .008). Only adolescents with AN demonstrated a significant increase in maximum postprandial diameter at repeat testing (P = .009). There was no difference in residual gastric volume between the 2 groups. Initial CSI scores were higher in adolescents with AN (P < .0001), including higher scores for nausea and abdominal pain. CSI scores were significantly lower in adolescents with AN (P = .035). Initial scores on the Screen for Child Anxiety-Related Emotional Disorders were significantly higher in adolescents with AN (P = .0005), but did not change over time. Adolescents with AN met significantly more criteria for FGIDs (P = .003).

conclusionAdolescents with AN have impaired gastric accommodation that improves after nutritional rehabilitation, have significantly more somatic complaints, and meet more criteria for anxiety disorders and FGIDs. After nutritional rehabilitation, somatization improves and FGIDs become less common, but symptoms of anxiety persist.

Indexed as

Gastric EmptyingAdolescentAnorexia NervosaAnxietyCase-Control StudiesChildFemaleFollow-Up StudiesGastrointestinal DiseasesHumansLinear ModelsLogistic ModelsProspective StudiesPsychological TestsSelf ReportSingle-Blind MethodANAnorexia nervosaBaseline/initial testingChildren's Somatization InventoryCSIFGIDFollow-up testingFunctional gastrointestinal disorderQPGS-RIIIQuestionnaire on Pediatric Gastrointestinal Symptoms–Rome III versionResidual gastric volumeRGVSCAREDScreen for Child Anxiety-Related Emotional DisordersT1T2

Identifiers

PMID23587435
PMCPMC3923459
OpenAlexW2045453338

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.