Evidence map›Paper›PMID 23587434›Full record

ArticleThe Journal of pediatrics2013

Increased risk of herpes zoster in children with asthma: a population-based case-control study.

Bong-Seong Kim, Sonia Mehra, Barbara Yawn, Charles Grose, Robert Tarrell, Brian Lahr, Young J Juhn

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  5. Atopic asthma as a potentially significant but unrecognized risk factor for Kawasaki disease in children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
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  9. A diagnostic codes-based algorithm improves accuracy for identification of childhood asthma in archival data sets.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021
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  12. Asthma increases the risk of herpes zoster: a nested case-control study using a national sample cohort.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Bong-Seong KimDepartment of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Sonia Mehra
Barbara Yawn
Charles Grose
Robert Tarrell
Brian Lahr
Young J Juhn
Mayo Clinic in Florida · USGangneung Asan Hospital · KROlmsted Medical Center · USUniversity of Iowa Stead Family Children’s Hospital · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Risk of Herpes Zoster Among Adults with AsthmaR21AI101277 · NIAID · MAYO CLINIC ROCHESTER · PI JUHN, YOUNG J · 2012 to 2013
$432k
NIAID NIH HHS R21 AI101277NIA NIH HHS R01 AG034676NIA NIH HHS R01 AG34676
6 · The paper itself

Abstract

objectiveTo determine the risk of herpes zoster (HZ) in children with and without asthma. STUDY

designThis study was designed as a population-based case-control study. We examined all children (aged <18 years) with possible HZ in Olmsted County, Minnesota, between 1996 and 2001 (n = 306; identified by International Classification of Diseases, Eighth Revision codes and predetermined criteria for HZ) to identify true cases. To determine the association between asthma and HZ, we compared the frequency of asthma among children with HZ with that among age- and sex-matched corresponding controls (1:1 matching) who resided in Olmsted County, Minnesota, during the study period. Asthma was ascertained based on predetermined criteria. A conditional logistic regression model was used to calculate ORs and 95% CIs.

resultsWe identified 277 eligible patients with HZ, 63 (23%) of whom had a history of asthma before the index date of HZ, compared with 35 of 277 (12.6%) matched controls (aOR, 2.09; 95% CI, 1.24-3.52; P = .006), adjusting for varicella vaccination and atopy status. The population-attributable risk percentage was 12%. Controlling for asthma and atopy status, varicella vaccination was associated with reduced risk of HZ (aOR, 0.44; 95% CI, 0.21-0.92; P = .028).

conclusionAsthma may be an unrecognized risk factor for reactivation of a non-airway-related latent infection such as HZ in children.

Indexed as

AdolescentAsthmaCase-Control StudiesChildChild, PreschoolFemaleHerpes ZosterHumansIncidenceInfantInfant, NewbornLogistic ModelsMaleMinnesotaOdds RatioRetrospective StudiesHerpes zosterHZ

Identifiers

PMID23587434
PMCPMC3728177
OpenAlexW1971207504

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.