ReviewBMC biology2013
Of flies and men: insights on organismal metabolism from fruit flies.
Review in BMC biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed.
- Diet impacts the effects of thermal stress on infection outcomes.BMC ecology and evolution · 2026Article
- Glucose is dynamically regulated by time of day in humans and Drosophila.PLoS biology · 2026Article
- Inter-organ communication in Drosophila: Lipoproteins, adipokines, and immune-metabolic coordination.Current opinion in cell biology · 2025Review
- Article
- Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases.Redox biology · 2025Review
- Undernutrition-induced stunting-like phenotype inNarra J · 2024Article
- Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis over a day:night cycle.bioRxiv : the preprint server for biology · 2024Article
- Flight to insight: maximizing the potential ofFrontiers in molecular neuroscience · 2024Article
- Starvation selection reduces and delays larval ecdysone production and signaling.The Journal of experimental biology · 2023Article
- A bacteria-regulated gut peptide determines host dependence on specific bacteria to support host juvenile development and survival.BMC biology · 2022Article
- 'Fly-ing' from rare to common neurodegenerative disease mechanisms.Trends in genetics : TIG · 2022Review
- Metabolic reprogramming in cancer: mechanistic insights from Drosophila.Disease models & mechanisms · 2021Review
- Metabolic control of daily locomotor activity mediated by tachykinin in Drosophila.Communications biology · 2021Article
- Redox regulation of the insulin signalling pathway.Redox biology · 2021Review
- What fuels the fly: Energy metabolism inScience advances · 2021Review
- A Superfamily-wide Activity Atlas of Serine Hydrolases inBiochemistry · 2021Article
- Domeless receptor loss in fat body tissue reverts insulin resistance induced by a high-sugar diet in Drosophila melanogaster.Scientific reports · 2021Article
- Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation inLife science alliance · 2021Article
- Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase.PloS one · 2021Article
- Insulin and Leptin/Upd2 Exert Opposing Influences on Synapse Number in Fat-Sensing Neurons.Cell metabolism · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The fruit fly Drosophila has contributed significantly to our general understanding of the basic principles of signaling, cell and developmental biology, and neurobiology. However, answers to questions pertaining to energy metabolism have been so far mostly addressed in more complex model organisms such as mice. We review in this article recent studies that show how the genetic tractability and simplicity of Drosophila are being used to identify novel regulatory mechanisms at the organismal level, and to query the co-ordination between energy metabolism and other processes such as neurodegeneration, circadian rhythms, immunity, and tumor biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.