Evidence map›Paper›PMID 23587025›Full record

ArticleJournal of anatomy2013

Elastic fibres are broadly distributed in tendon and highly localized around tenocytes.

Tyler M Grant, Mark S Thompson, Jill Urban, Jing Yu

Open access · greenAbstract read
In one paragraph

Article in Journal of anatomy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Grafts in tendon repair.Materials today. Bio · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Elastic fibers in orthopedics: Form and function in tendons and ligaments, clinical implications, and future directions.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Review
  14. Article
  15. In Vitro Innovation of Tendon Tissue Engineering Strategies.International journal of molecular sciences · 2020
    Review
  16. Article
  17. Review
  18. The "other" 15-40%: The Role of Non-Collagenous Extracellular Matrix Proteins and Minor Collagens in Tendon.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Review
  19. Article
  20. Load transfer, damage, and failure in ligaments and tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tyler M GrantDepartment of Engineering, Science, Institute of Biomedical Engineering, University of Oxford, Oxford, UK. tyler.grant@chch.ox.ac.uk
Mark S Thompson
Jill Urban
Jing Yu
University of Oxford · GBScience Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elastic fibres have the unique ability to withstand large deformations and are found in numerous tissues, but their organization and structure have not been well defined in tendon. The objective of this study was to characterize the organization of elastic fibres in tendon to understand their function. Immunohistochemistry was used to visualize elastic fibres in bovine flexor tendon with fibrillin-1, fibrillin-2 and elastin antibodies. Elastic fibres were broadly distributed throughout tendon, and highly localized longitudinally around groups of cells and transversely between collagen fascicles. The close interaction of elastic fibres and cells suggests that elastic fibres are part of the pericellular matrix and therefore affect the mechanical environment of tenocytes. Fibres present between fascicles are likely part of the endotenon sheath, which enhances sliding between adjacent collagen bundles. These results demonstrate that elastic fibres are highly localized in tendon and may play an important role in cellular function and contribute to the tissue mechanics of the endotenon sheath.

Indexed as

AnimalsCattleElastic TissueElastinFibrillinsFootImmunohistochemistryMaleMicrofilament ProteinsMicroscopyTendonsElastinFibrillinsMicrofilament Proteins

Identifiers

PMID23587025
PMCPMC3666236
OpenAlexW2015983515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.