ArticleThe Angle orthodontist2013
Virulence modulation of Streptococcus mutans biofilms by metal ions released from orthodontic appliances.
Article in The Angle orthodontist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Anti-Cariogenic Potential of Lyophilized Cell-Free Supernatant of ProbioticJournal of microbiology and biotechnology · 2026Article
- Photoinactivation of multispecies cariogenic biofilm mediated by aluminum phthalocyanine chloride encapsulated in chitosan nanoparticles.Lasers in medical science · 2022Article
- Effects of Caries Activity on Compositions of Mutans Streptococci in Saliva-Induced Biofilm Formed on Bracket Materials.Materials (Basel, Switzerland) · 2020Article
- Effect of Different Glucose Concentrations on Small RNA Levels and Adherence of Streptococcus mutans.Current microbiology · 2019Article
- Acquisition and maturation of oral microbiome throughout childhood: An update.Dental research journal · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the impact of metal ions commonly shed from orthodontic appliances on the virulence of Streptococcus mutans ATCC®25175™ biofilms. MATERIALS AND
methodsBiofilms were grown in the presence of Ni(2+), Fe(3+), Cr(3+), Co(2+), and a metal ion pool at concentrations similar to those released in saliva of orthodontic patients for 72 hours. Once mature, biofilms were treated for up to 12 hours with 5% glucose.
resultsIons interfered with the growth of S mutans by reducing its biomass (Ni(2+), Fe(3+), Cr(3+)), raising its rates of sugar metabolism (Ni(2+), Fe(3+), Cr(3+)), and raising its secretion of lactate (Ni(2+), Fe(3+), Cr(3+), pool).
conclusionThe laboratory data presented here point to the possibility of virulence increase of S mutans by metal ions commonly released during orthodontic therapy.
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Registered trials
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