Evidence map›Paper›PMID 23586037›Full record

ReviewBioMed research international2013

Diet, microbiome, and the intestinal epithelium: an essential triumvirate?

Javier Rivera Guzman, Victoria Susan Conlin, Christian Jobin

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Extracellular Vesicles-Oral Therapeutics of the Future.International journal of molecular sciences · 2022
    Review
  14. Fermentation Supernatants ofMicroorganisms · 2021
    Article
  15. Article
  16. Article
  17. Mitochondrial function - gatekeeper of intestinal epithelial cell homeostasis.Nature reviews. Gastroenterology & hepatology · 2018
    Review
  18. Human microbiota, blood group antigens, and disease.Wiley interdisciplinary reviews. Systems biology and medicine · 2018
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Javier Rivera GuzmanDepartment of Pharmacology, University of North Carolina School of Medicine, CB 7032, 103 Mason Farm Road, Chapel Hill, NC 27599, USA.
Victoria Susan Conlin
Christian Jobin
University of North Carolina at Chapel Hill · US

Funding

SEEDING POSTDOCTORAL INNOVATORS IN RESEARCH &EDUCATIONK12GM000678 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DONALD T LYSLE, Kathryn Joanna Reissner · 1999 to 2026
$30.9M
The role of klebsiella pneumonia-derived colibactin in colitis-associated colon cancerR01DK073338 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOBIN, CHRISTIAN · 2007 to 2023
$5.4M
REGULATION OF IMMUNOSUPPRESSIVE MOLECULES IN IBDR01DK047700 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOBIN, CHRISTIAN · 1993 to 2014
$3.2M
NIDDK NIH HHS R01 DK047700NIDDK NIH HHS R01DK047700NIDDK NIH HHS R01 DK073338NIDDK NIH HHS R01DK073338NIGMS NIH HHS K12 GM000678NIGMS NIH HHS K12GM000678
6 · The paper itself

Abstract

The intestinal epithelium represents a critical barrier protecting the host against diverse luminal noxious agents, as well as preventing the uncontrolled uptake of bacteria that could activate an immune response in a susceptible host. The epithelial monolayer that constitutes this barrier is regulated by a meshwork of proteins that orchestrate complex biological function such as permeability, transepithelial electrical resistance, and movement of various macromolecules. Because of its key role in maintaining host homeostasis, factors regulating barrier function have attracted sustained attention from the research community. This paper will address the role of bacteria, bacterial-derived metabolism, and the interplay of dietary factors in controlling intestinal barrier function.

Indexed as

DietMetagenomeBacteriaBacterial InfectionsGastrointestinal TractHomeostasisHumansIntestinal MucosaProbiotics

Identifiers

PMID23586037
PMCPMC3613061
OpenAlexW2097395280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.