ReviewBioMed research international2013
Structures and properties of naturally occurring polyether antibiotics.
Review in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 122 citations in OpenAlex.
- Genome-directed discovery of an octalin-containing polyether ionophore improves diabetic skin wound healing.Nature communications · 2026Article
- Copper(II), a Peculiar Metal Ion for Complexation With Monensin A Ionophore.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Affinity-based protein profiling of the antiviral natural product nanchangmycin.RSC chemical biology · 2026Article
- Overproduction of endusamycin inSynthetic and systems biotechnology · 2025Article
- Low-Dose Salinomycin Alters Mitochondrial Function and Reprograms Global Metabolism in Burkitt Lymphoma.International journal of molecular sciences · 2025Article
- Natural products as transmission-blocking agents against malaria: a comprehensive review of bioactive compounds and their therapeutic potential.Malaria journal · 2025Review
- From Pseudocyclic to Macrocyclic Ionophores: Strategies toward the Synthesis of Cyclic Monensin Derivatives.The Journal of organic chemistry · 2025Article
- Article
- Article
- Replenishment of mitochondrial NaMaterials today. Bio · 2024Article
- Chemistry and biology of specialized metabolites produced byNatural product reports · 2024Review
- Polyether ionophore resistance in a one health perspective.Frontiers in microbiology · 2024Review
- Spectroscopic, Spectrometric and Computational Studies of New Lasalocid Derivatives and Their Complexes with Selected Metal Cations.Molecules (Basel, Switzerland) · 2023Article
- New Hydrophilic Derivatives of Lasalocid and Their Complexes with Selected Metal Cations.Molecules (Basel, Switzerland) · 2023Article
- Extraction, Isolation, Characterization, and Bioactivity of Polypropionates and Related Polyketide Metabolites from the Caribbean Region.Antibiotics (Basel, Switzerland) · 2023Review
- Epoxide-Based Synthetic Approaches toward Polypropionates and Related Bioactive Natural Products.International journal of molecular sciences · 2023Review
- C-N bond formation by a polyketide synthase.Nature communications · 2023Article
- Targeting Multiple Homeostasis-Maintaining Systems by Ionophore Nigericin Is a Novel Approach for Senolysis.International journal of molecular sciences · 2022Article
- In Vitro Antiparasitic Activities of Monovalent Ionophore Compounds for Human and Canine Leishmaniases.Animals : an open access journal from MDPI · 2022Article
- The Rare ActinobacteriumMicroorganisms · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyether ionophores represent a large group of natural, biologically active substances produced by Streptomyces spp. They are lipid soluble and able to transport metal cations across cell membranes. Several of polyether ionophores are widely used as growth promoters in veterinary. Polyether antibiotics show a broad spectrum of bioactivity ranging from antibacterial, antifungal, antiparasitic, antiviral, and tumour cell cytotoxicity. Recently, it has been shown that some of these compounds are able to selectively kill cancer stem cells and multidrug-resistant cancer cells. Thus, they are recognized as new potential anticancer drugs. The biological activity of polyether ionophores is strictly connected with their molecular structure; therefore, the purpose of this paper is to present an overview of their formula, molecular structure, and properties.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.