ArticleJournal of thoracic disease2013
Analysis of antimicrobial resistance and class 1 integrons among strains from upper respiratory tract of healthy adults.
Article in Journal of thoracic disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Clonal Dissemination of Pandrug-ResistantInternational journal of molecular sciences · 2025Article
- Respiratory tract bacteria distribution and transmission patterns among individuals in close contact.BMC infectious diseases · 2024Article
- Virulence Signatures, Integrons, and Antibiotic Resistance Genes in Bacterial Strains Recovered from Selected Commercial Dairy Products and Fresh Raw Meat.Current microbiology · 2023Article
- Distribution of pathogenic bacteria in lower respiratory tract infection in lung cancer patients after chemotherapy and analysis of integron resistance genes in respiratory tract isolates of uninfected patients.Journal of thoracic disease · 2020Article
- Detection of New Delhi metallo-beta-lactamase enzyme geneAccess microbiology · 2020Article
- Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution.The ISME journal · 2015Review
- Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age.The ISME journal · 2015Article
- Detection of Class I Integrons in Staphyloacoccus aurous Isolated From Clinical Samples.Iranian Red Crescent medical journal · 2014Article
- Integrons: past, present, and future.Microbiology and molecular biology reviews : MMBR · 2014Review
- Identification of antibiotic resistance cassettes in class 1 integrons in Aeromonas spp. strains isolated from fresh fish (Cyprinus carpio L.).Current microbiology · 2014Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe distribution and characterization of integrons among opportunistic pathogens from nasopharynx of healthy adults.
methodsA total of 1,019 nasopharyngeal samples from healthy adults were collected; bacteria were identified by API system; antibiotic susceptibility were tested by K-B method; class 1, 2 and 3 integrons were examined by degenerate primers of the genetic content of integrons were analyzed by PCR and DNA sequencing.
resultsOut of the 1,019 cases, 743 (72.9%) opportunistic pathogens were isolated. The top five commons organism identified were Coagulase-negative staphylococcus (n=404), Staphylococcus aureus (n=109), Haemophilus influenzae (n=74), Streptococcus pneumoniae (n=49) and Klebsiella pneumoniae (n=32). Eight (25.0%) isolates of K. pneumoniae produced the ESBLs. The isolated rates of S. aureus and H. influenzae were decreased with aging. 6.3% (2/32) K. pneumoniae isolates and 16.7% (1/8) Proteus isolates carried class 1 integrons. Among intI1-positive strains, sequencing analysis revealed that one of the integron positive K. pneumoniae isolates harbored gene cassette aadA5-dfrA17. Proteus isolates harbored gene cassette aadA2-dhfrXII.
conclusionsThe results stressed the need for continued surveillance of bacteria from the asymptomatic carriers.
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