Evidence map›Paper›PMID 23585772›Full record

ArticleExpert review of ophthalmology2012

Scaffolds and stem cells: delivery of cell transplants for retinal degenerations.

Karl E Kador, Jeffrey L Goldberg

Open access · greenAbstract read
In one paragraph

Article in Expert review of ophthalmology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
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  3. Review
  4. Article
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  7. Article
  8. Article
  9. Review
  10. Pluripotent stem cell therapy for retinal diseases.Annals of translational medicine · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Immunocytochemical Profiling of Cultured Mouse Primary Retinal Cells.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2017
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karl E KadorBascom Palmer Eye Institute and Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, 1501 NW 10th Avenue, BRB 826, FL 33136, USA.
Jeffrey L Goldberg
Stem Cell Institute · PA

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Retinal Scaffolds: Synaptic and Stem Cell IntegrationRC1EY020297 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GOLDBERG, JEFFREY L · 2009 to 2010
$763k
NEI NIH HHS P30 EY014801NEI NIH HHS RC1 EY020297
6 · The paper itself

Abstract

Retinal degenerations and optic neuropathies often lead to death of photoreceptors or retinal ganglion cells, respectively. Stem cell therapies are showing promise for these diseases in preclinical models and are beginning to transition into human trials, but cell delivery and integration remain major challenges. Focusing on photoreceptor- and progenitor-directed approaches, in this article, the authors review how advances in tissue engineering and cell scaffold design are enhancing cell therapies for retinal degeneration.

Indexed as

photoreceptorprogenitor cellscaffoldstem celltissue engineeringtransplantation

Identifiers

PMID23585772
PMCPMC3622368
OpenAlexW2055186179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.