ArticleClinical cardiology2013
Dissociation between severity of takotsubo cardiomyopathy and presentation with shock or hypotension.
Article in Clinical cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 47 citations in OpenAlex.
- Mechanical circulatory support for cardiogenic shock in takotsubo syndrome.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Ventricular-Arterial Coupling in Takotsubo Syndrome: Controversies and Opportunities.Journal of cardiovascular development and disease · 2026Article
- Prospective comparison of temporal changes in myocardial function in women with Takotsubo versus anterior STEMI.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Observational
- Incidence and clinical/laboratory correlates of early hypotension in takotsubo syndrome.ESC heart failure · 2021Article
- Takotsubo Syndrome: Clinical Manifestations, Etiology and Pathogenesis.Current cardiology reviews · 2021Article
- Prolonged suppression of the anti-oxidant/anti-inflammatory effects of BNP post-Takotsubo syndrome.ESC heart failure · 2020Article
- Stress cardiomyopathy induced during dobutamine stress echocardiography.International journal of critical illness and injury science · 2020Article
- Review
- Implications of Left Bundle Branch Block in Takotsubo Cardiomyopathy: Propensity Match Analysis from the National Inpatient Sample.Cardiology and therapy · 2019Article
- Role of echocardiography for takotsubo cardiomyopathy: clinical and prognostic implications.Cardiovascular diagnosis and therapy · 2018Review
- Takotsubo triggered by acute myocardial infarction: a common but overlooked syndrome?Journal of geriatric cardiology : JGC · 2014Article
- Reply: To PMID 23585361.Clinical cardiology · 2013Article
- Response to Dissociation between severity of takotsubo cardiomyopathy and presentation with shock or hypotension.Clinical cardiology · 2013Article
- Response to dissociation between severity of Takotsubo cardiomyopathy and presentation with shock or hypotension.Clinical cardiology · 2013Article
- Letters to the editor.Clinical cardiology · 2013Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTakotsubo cardiomyopathy (TTC) is increasingly well-recognized as a cause of chest-pain syndromes, especially in aging females. The most common complications of TTC occur in the first 24 hours post onset of symptoms and include shock and/or arrhythmias. HYPOTHESIS: We tested the hypothesis that the severity of early hypotension in TTC reflects the extent of myocardial involvement and dysfunction.
methodsIn 80 consecutive TTC patients, correlates of blood pressure on the day of admission were sought via univariate followed by multivariate analysis.
resultsMean systolic blood pressure (SBP) on day 1 was 120 ± 24 (SD) mm Hg. During the first 3 days of admission, 39% of patients had SBP <90 mm Hg, and 9% died and/or required intra-aortic balloon pump insertion. The extent of release of N-terminal pro-brain natriuretic peptide, with its potential correlate of associated vasodilator activity, varied inversely with pulmonary-artery saturation, a measure of cardiac output. However, there was no significant relationship between normetanephrine release and SBP. On multivariate analyses there was no significant relationship between SBP and (1) wall-motion score index (as an index of left-ventricular systolic dysfunction) or (2) T2 enhancement on cardiac magnetic resonance imaging and peak N-terminal pro-brain natriuretic peptide (as indices of myocardial inflammation).
conclusionsAlthough severe hypotension and shock occur commonly during acute stages of TTC, these complications are multifactorial in origin, probably representing a combination of impaired inotropic state and vasodilatation. Importantly, initial hypotension does not imply severe left ventricular inflammation or systolic dysfunction.
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