ReviewJournal of cardiovascular translational research2013
Evaluation of right and left ventricular diastolic filling.
Review in Journal of cardiovascular translational research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Advanced Imaging Technologies for Assessing Tetralogy of Fallot: Insights Into Flow Dynamics.CJC pediatric and congenital heart disease · 2023Review
- Computational Modeling of Right Ventricular Motion and Intracardiac Flow in Repaired Tetralogy of Fallot.Cardiovascular engineering and technology · 2022Article
- Ventricular flow analysis and its association with exertional capacity in repaired tetralogy of Fallot: 4D flow cardiovascular magnetic resonance study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Article
- Moving beyond size: vorticity and energy loss are correlated with right ventricular dysfunction and exercise intolerance in repaired Tetralogy of Fallot.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Effect of diastolic dysfunction on intraventricular velocity behavior in early diastole by flow mapping.The international journal of cardiovascular imaging · 2019Article
- Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 2: Pluridisciplinary perspective on their genetic and molecular origins.Journal of molecular and cellular cardiology · 2019Review
- Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 1: Pluridisciplinary perspective on their hemodynamics and morphomechanics.Journal of molecular and cellular cardiology · 2019Article
- Left ventricular vortex and intraventricular pressure difference in dogs under various loading conditions.American journal of physiology. Heart and circulatory physiology · 2019Article
- Morphomechanic phenotypic variability of sarcomeric cardiomyopathies: A multifactorial polygenic perspective.Journal of molecular and cellular cardiology · 2019Review
- Challenges and Controversies in Hypertrophic Cardiomyopathy: Clinical, Genomic and Basic Science Perspectives.Revista espanola de cardiologia (English ed.) · 2018Article
- Implementing genome-driven personalized cardiology in clinical practice.Journal of molecular and cellular cardiology · 2018Review
- Feasibility of Computational Fluid Dynamics for Evaluating the Intraventricular Hemodynamics in Single Right Ventricle Based on Echocardiographic Images.BioMed research international · 2018Article
- Know Me! Unraveling the Riddle of Calcific Aortic Valve Disease by Bioinformatics.The Tohoku journal of experimental medicine · 2017Article
- Relationship between the abnormal diastolic vortex structure and impaired left ventricle filling in patients with hyperthyroidism.Medicine · 2017Article
- Genomic translational research: Paving the way to individualized cardiac functional analyses and personalized cardiology.International journal of cardiology · 2017Review
- Patient-specific CFD simulation of intraventricular haemodynamics based on 3D ultrasound imaging.Biomedical engineering online · 2016Article
- Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions.Journal of cardiovascular translational research · 2015Review
- Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2.Journal of cardiovascular translational research · 2015Article
- Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1.Journal of cardiovascular translational research · 2015Review
- Vortex formation time is not an index of ventricular function.Journal of cardiovascular translational research · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
A conceptual fluid-dynamics framework for diastolic filling is developed. The convective deceleration load (CDL) is identified as an important determinant of ventricular inflow during the E wave (A wave) upstroke. Convective deceleration occurs as blood moves from the inflow anulus through larger-area cross-sections toward the expanding walls. Chamber dilatation underlies previously unrecognized alterations in intraventricular flow dynamics. The larger the chamber, the larger becomes the endocardial surface and the CDL. CDL magnitude affects strongly the attainable E wave (A wave) peak. This underlies the concept of diastolic ventriculoannular disproportion. Large vortices, whose strength decreases with chamber dilatation, ensue after the E wave peak and impound inflow kinetic energy, averting an inflow-impeding, convective Bernoulli pressure rise. This reduces the CDL by a variable extent depending on vortical intensity. Accordingly, the filling vortex facilitates filling to varying degrees, depending on chamber volume. The new framework provides stimulus for functional genomics research, aimed at new insights into ventricular remodeling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.