Evidence map›Paper›PMID 23585216›Full record

ReviewCurrent allergy and asthma reports2013

House dust mite interactions with airway epithelium: role in allergic airway inflammation.

Vivek D Gandhi, Courtney Davidson, Muhammad Asaduzzaman, Drew Nahirney, Harissios Vliagoftis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Sex chromosomes and gonadal sex interactions in airway and immune responses to allergen challenge.American journal of physiology. Lung cellular and molecular physiology · 2026
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  9. Production ofJournal of immunology research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vivek D GandhiPulmonary Research Group, Department of Medicine, University of Alberta, 567 HMRC, Edmonton, AB T6G 2S2, Canada. vivekdip@ualberta.ca
Courtney Davidson
Muhammad Asaduzzaman
Drew Nahirney
Harissios Vliagoftis
University of Alberta · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

House dust mite (HDM) allergens are the most prevalent allergens associated with asthma and rhinitis around the world. The mechanisms of allergic sensitization and allergic airway inflammation after exposure to HDM have been studied extensively, but many questions remain unanswered. Airway epithelial cells are the first line of defense against external antigens and are considered an important player in the development of allergic airway inflammation. Both genetic susceptibility to allergic sensitization and HDM composition play decisive roles in the outcome of HDM-epithelium interactions, especially regarding airway epithelial dysfunction and allergic inflammation. Interactions between HDM and the airway epithelium have consequences for both development of allergy and asthma and development of allergic airway inflammation. This review will describe in detail these interactions and will identify issues that require more study.

Indexed as

AllergensAnimalsAntigens, DermatophagoidesAsthmaDermatophagoides pteronyssinusHumansHypersensitivityInflammation MediatorsRespiratory MucosaAllergensAntigens, DermatophagoidesInflammation Mediators

Identifiers

PMID23585216
OpenAlexW1996995272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.