ArticleClinical research in cardiology : official journal of the German Cardiac Society2013
Increased pericardial adipose tissue is correlated with atrial fibrillation and left atrial dilatation.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Pooled it
- Epicardial Adipose Tissue Volume and Left Atrial Remodeling: A J-Shaped Association in Older Adults.Journal of cardiovascular development and disease · 2026Article
- Longitudinal associations of the alternative healthy eating index with coronary artery calcification and pericardial adiposity in US adults with and without type 1 diabetes.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024Article
- Impact of Obesity on Atrial Electrophysiological Substrate.Journal of cardiovascular development and disease · 2023Review
- Development and Validation of a Machine Learning-Based Radiomics Model on Cardiac Computed Tomography of Epicardial Adipose Tissue in Predicting Characteristics and Recurrence of Atrial Fibrillation.Frontiers in cardiovascular medicine · 2022Article
- Effect of epicardial fat volume on outcomes after left atrial posterior wall isolation in addition to pulmonary vein isolation in patients with persistent atrial fibrillation.Frontiers in cardiovascular medicine · 2022Article
- The Predictive Value of Epicardial Fat Tissue Volume in the Occurrence and Development of Atrial Fibrillation: A Systematic Review and Meta-Analysis.Cardiology research and practice · 2022Review
- Impaired fasting glucose: a risk factor for atrial fibrillation and heart failure.Cardiovascular diabetology · 2021Article
- New Insights on the Role of Connexins and Gap Junctions Channels in Adipose Tissue and Obesity.International journal of molecular sciences · 2021Review
- Increased Pericardial Adipose Tissue in Smokers.Journal of clinical medicine · 2021Article
- Cardiac Adiposity and Arrhythmias: The Role of Imaging.Diagnostics (Basel, Switzerland) · 2021Review
- Association of pericardial adipose tissue with left ventricular structure and function: a region-specific effect?Cardiovascular diabetology · 2021Article
- Difference in epicardial adipose tissue distribution between paroxysmal atrial fibrillation and coronary artery disease.Heart and vessels · 2020Observational
- Pericardial adipose tissue is an independent risk factor of coronary artery disease and is associated with risk factors of coronary artery disease.The Journal of international medical research · 2020Article
- Obesity and metabolic features associated with long-term developing diastolic dysfunction in an initially healthy population-based cohort.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Article
- Article
- Increased Ca buffering underpins remodelling of CaThe Journal of physiology · 2017Article
- Relation of Pericardial Fat, Intrathoracic Fat, and Abdominal Visceral Fat With Incident Atrial Fibrillation (from the Framingham Heart Study).The American journal of cardiology · 2016Article
- Differences between perivascular adipose tissue surrounding the heart and the internal mammary artery: possible role for the leptin-inflammation-fibrosis-hypoxia axis.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
- Monocyte-platelet aggregates and CD11b expression as markers for thrombogenicity in atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPericardial adipose tissue (PAT), a visceral fat depot surrounding the heart, serves as an endocrine active organ and is associated with inflammation. There is growing evidence that atrial fibrillation (AF) is linked with inflammation, which in turn can be a promoter of left atrial remodeling. The aim of this study was to evaluate a potential correlation of PAT to AF and left atrial structural remodeling represented by LA size.
methodsPAT was measured in 1,288 patients who underwent coronary artery calcium-scanning for coronary risk stratification. LA size was determined by two independent readers. Patients were subdivided into patients without AF, patients with paroxysmal and persistent AF.
resultsPAT was independently correlated with AF, persistent AF, and LA size (all p values <0.001). No association could be observed between paroxysmal AF and PAT. These associations persisted after multivariate adjustment for AF risk factors such as age, hypertension, valvular disease, heart failure, and body mass index (AF: OR 1.52, 95 % CI 1.15-2.00, p = 0.003; persistent AF: OR 2.58, 95 % CI 1.69-3.99, p = 0.001; LA size: regression coefficient 0.15 with 95 % CI 0.10-0.20, p < 0.001).
conclusionPAT is associated with AF, in particular with persistent AF and LA size. These findings suggest that PAT could be an independent risk factor for the development of AF and for LA remodeling.
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