ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2013
Advancement in the routine identification of anaerobic bacteria by MALDI-TOF mass spectrometry.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Application of MALDI-TOF MS to rapid identification of anaerobic bacteria.BMC infectious diseases · 2019Pooled it
- Matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) for identification of anaerobic and microaerophilic bacteria from clinical specimens, in comparison with conventional techniques.Iranian journal of microbiology · 2026Article
- MALDI-TOF MS, following separation gel coagulation tubes and short-term solid phase culture effectively detects pathogenic microbes from positive blood cultures.Open medicine (Warsaw, Poland) · 2026Article
- Vertebral osteomyelitis caused byIDCases · 2023Article
- Culturomics Approaches Expand the Diagnostic Accuracy for Sexually Transmitted Infections.International journal of molecular sciences · 2021Review
- Innovative and Highly Sensitive Detection ofToxins · 2021Article
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- Pathogenic potential ofBMJ case reports · 2020Article
- Direct Identification and Antimicrobial Susceptibility Testing of Bacteria From Positive Blood Culture Bottles by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and the Vitek 2 System.Annals of laboratory medicine · 2016Article
- Article
- Use of MALDI-TOF MS for Identification of Nontuberculous Mycobacterium Species Isolated from Clinical Specimens.BioMed research international · 2015Article
- C. difficile ribotype 027 or 176?Folia microbiologica · 2014Article
- Advanced mass spectrometry technologies for the study of microbial pathogenesis.Current opinion in microbiology · 2014Article
- MALDI-TOF MS versus VITEK 2 ANC card for identification of anaerobic bacteria.Journal of thoracic disease · 2014Article
- The first case of Eggerthella lenta bacteremia in Korea.Annals of laboratory medicine · 2014Article
- Clostridium difficile.Clinics in laboratory medicine · 2010Review
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9 authors.
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Abstract
We evaluated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) Biotyper as a tool for the identification of anaerobic bacteria compared with 500 base-pair (bp) 16S ribosomal ribonucleic acid (rRNA) gene sequencing analysis, which is considered to be the "gold standard" method. A total of 484 anaerobic bacteria were retrieved from the clinical specimens of 318 pediatric patients. Molecular identification resulted in 18 genera and 51 species. The most prevalent genus was Clostridium (76.85 %), with 70 % C. difficile isolates. The concordance and sensitivity determined by MALDI-TOF MS for C. difficile, the most prevalent species isolated, was 94.08 %, whereas the specificity was 100 %. For the other anaerobes, the sensitivity and specificity were 94.07 % and 81.82 %, respectively, with a concordance of 93.15 %. Low performance was observed for Propionibacterium acnes and Fusobacterium nucleatum, for which a dedicated pretreatment procedure should likely be set up. MALDI-TOF MS was shown to be a valid alternative for the fast and reliable identification of the most clinically relevant anaerobic bacteria; moreover, it is less time-consuming, the cost for reagents is minimized, and it does not require dedicated personnel.
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