Evidence map›Paper›PMID 23584439›Full record

ArticleBone marrow transplantation2013

Hematopoietic SCT in Europe: data and trends in 2011.

J R Passweg, H Baldomero, M Bregni, S Cesaro, P Dreger, R F Duarte, J H F Falkenburg, N Kröger, D Farge-Bancel, H Bobby Gaspar and 8 more

Registry-linked trialAbstract readHistorical Article
In one paragraph

Article in Bone marrow transplantation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03113162 (Evaluation of the Safety and Efficacy of Reduced-intensity Immunoablation and Autologous Hematopoietic Stem Cell Transplantation), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03113162 phase1unknown statusnot on this mapstarted 2015, after this paper: background citation

Evaluation of the Safety and Efficacy of Reduced-intensity Immunoablation and Autologous Hematopoietic Stem Cell Transplantation (AHSCT) in Multiple Sclerosis

TypeinterventionalSponsorMakati Medical CenterRan2015 to 2022Enrolled15ConditionsMultiple SclerosisArmsAutologous Hematopoietic Stem Cell, BEAM Regimen
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Determinants of exercise adherence and contamination in a randomized controlled trial in cancer patients during and after allogeneic HCT.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

J R PasswegEBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital, Basel, Switzerland.
H Baldomero
M Bregni
S Cesaro
P Dreger
R F Duarte
J H F Falkenburg
N Kröger
D Farge-Bancel
H Bobby Gaspar
J Marsh
M Mohty
C Peters
A Sureda
A Velardi
C Ruiz de Elvira
A Madrigal
European Group for Blood and Marrow Transplantation

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all, 651 from 680 centers in 48 countries reported 35 660 hematopoietic SCT (HSCT) in 32 075 patients (13 470 allogeneic (42%), 18 605 autologous (58%)) to the 2011 survey. Main indications were: leukemias; 10 113 (32%; 94% allogeneic); lymphoid neoplasias; non-Hodgkin's lymphoma, Hodgkin's lymphoma, plasma cell disorders; 18 433 (57%; 12% allogeneic); solid tumours; 1573 (5%; 5% allogeneic); and non-malignant disorders; 1830 (6%; 92% allogeneic). There were more unrelated donors than HLA identical sibling donors (54% versus 39%); proportion of peripheral blood as stem cell source was 99% for autologous and 73% for allogeneic HSCT. Cord blood was only used in allogeneic transplants (6% of total). In the past 10 years, the overall number of transplants has increased by 53%. Allogeneic HSCT have doubled (from 7272 to 14 549) while, autologous have increased by 32% and continue to increase by about 1100 HSCT per year since 2001. In the past 2 years, an increase of >2000 HSCT per year was seen. Transplant activity is shown by team size. For allogeneic HSCT, we show use of reduced-intensity conditioning versus myeloablative conditioning across Europe and use of post-transplant donor lymphocyte infusions with considerable variation across different countries.

Indexed as

EuropeHematopoietic Stem Cell TransplantationHistory, 21st CenturyHumansTransplantation, AutologousTransplantation, Homologous

Identifiers

PMID23584439
PMCPMC3763517

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.