Evidence map›Paper›PMID 23584197›Full record

ArticleChannels (Austin, Tex.)

Recovery from slow inactivation of Shab K(+) channels.

Imilla I Arias-Olguín, Elisa Carrillo, Leon D Islas, Froylan Gómez-Lagunas

Abstract readComment
In one paragraph

Article in Channels (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Imilla I Arias-OlguínDepartamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, México D.F., México.
Elisa Carrillo
Leon D Islas
Froylan Gómez-Lagunas

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have recently examined slow inactivation of Shab channels. Here we extend our characterization of Shab slow inactivation by presenting the properties of recovery from inactivation. The observations support our proposal that Shab reaches the same inactivated state either from open or closed states and suggest that closed and open state inactivation share the same mechanism. Regarding the latter, we also show that external K (+) and TEA slow down recovery from inactivation in agreement with the hypothesis that the mechanism of Shab inactivation qualitatively differs from C-type inactivation.

Indexed as

AnimalsCalciumNitric OxidePurkinje CellsRyanodine Receptor Calcium Release ChannelCalciumNitric OxideRyanodine Receptor Calcium Release ChannelDrosophilaShab K+ channelsslow inactivationU-type inactivation

Identifiers

PMID23584197
PMCPMC3710351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.