Evidence map›Paper›PMID 23584093›Full record

ArticleTranscription

Transient Mesp1 expression: a driver of cardiac cell fate determination.

Yu Liu, Robert J Schwartz

Open access · bronzeAbstract read
In one paragraph

Article in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. How Mesp1 makes a move.The Journal of cell biology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Yu LiuDepartment of Biology and Biochemistry; University of Houston; Houston, TX USA.
Robert J Schwartz
University of Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesp1 sits on the tip of the cardiac regulatory hierarchy, recent evidences support that it is regulated by stem cell factor Oct4, early gastrulation signal canonical Wnts and a couple of T-box factors, T and Eomes. With other transcription factors, Mesp1 programs/reprograms human cells toward cardiomyocytes.

Indexed as

Basic Helix-Loop-Helix ProteinsCell DifferentiationCellular ReprogrammingEmbryonic Stem CellsHumansMyocytes, CardiacOctamer Transcription Factor-3Promoter Regions, GeneticProtein BindingProto-Oncogene Protein c-ets-2Wnt ProteinsBasic Helix-Loop-Helix ProteinsETS2 protein, humanMESP1 protein, humanOctamer Transcription Factor-3POU5F1 protein, humanProto-Oncogene Protein c-ets-2Wnt Proteinsembryonic stem cellsMesp1progenitor cellsreprogramingtranscription factor

Identifiers

PMID23584093
PMCPMC4042590
OpenAlexW2116832144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.