Evidence map›Paper›PMID 23583964›Full record

ReviewInternational journal of environmental research and public health2013

Arsenic-induced genotoxicity and genetic susceptibility to arsenic-related pathologies.

Francesca Faita, Liliana Cori, Fabrizio Bianchi, Maria Grazia Andreassi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 139 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Unravelling the developmental toxicity of heavy metals using zebrafish as a model: a narrative review.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Arsenic in Mining Areas: Environmental Contamination Routes.International journal of environmental research and public health · 2023
    Article
  13. Review
  14. Unboxing the molecular modalities of mutagens in cancer.Environmental science and pollution research international · 2022
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. A Single Microbiome Gene Alters Murine Susceptibility to Acute Arsenic Exposure.Toxicological sciences : an official journal of the Society of Toxicology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francesca FaitaInstitute of Clinical Physiology, CNR, via Moruzzi 1, Pisa 56124, Italy. francesca.faita@ifc.cnr.it
Liliana Cori
Fabrizio Bianchi
Maria Grazia Andreassi
Istituto di Fisiologia Clinica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The arsenic (As) exposure represents an important problem in many parts of the World. Indeed, it is estimated that over 100 million individuals are exposed to arsenic, mainly through a contamination of groundwaters. Chronic exposure to As is associated with adverse effects on human health such as cancers, cardiovascular diseases, neurological diseases and the rate of morbidity and mortality in populations exposed is alarming. The purpose of this review is to summarize the genotoxic effects of As in the cells as well as to discuss the importance of signaling and repair of arsenic-induced DNA damage. The current knowledge of specific polymorphisms in candidate genes that confer susceptibility to arsenic exposure is also reviewed. We also discuss the perspectives offered by the determination of biological markers of early effect on health, incorporating genetic polymorphisms, with biomarkers for exposure to better evaluate exposure-response clinical relationships as well as to develop novel preventative strategies for arsenic-health effects.

Indexed as

Genetic Predisposition to DiseaseArsenicDNA DamageEnvironmental PollutantsHumansPolymorphism, GeneticArsenicEnvironmental Pollutants

Identifiers

PMID23583964
PMCPMC3709332
OpenAlexW2018682497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.