Evidence map›Paper›PMID 23583467›Full record

ReviewClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2013

Acute kidney injury in patients with cirrhosis: perils and promise.

Justin M Belcher, Chirag R Parikh, Guadalupe Garcia-Tsao

Abstract readCase ReportsReview
In one paragraph

Review in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Serum IL-6 as a marker of disease progression in interstitial nephritis.American journal of translational research · 2022
    Article
  9. Baseline serum cystatin C as a marker of acute kidney injury in patients with acute-on-chronic liver failure.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Observational
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Beneficial and harmful effects of nonselective beta blockade on acute kidney injury in liver transplant candidates.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2017
    Article
  18. Review
  19. Reduced impact of renal failure on the outcome of patients with alcoholic liver disease undergoing liver transplantation.Liver international : official journal of the International Association for the Study of the Liver · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Justin M BelcherProgram of Applied Translational Research, Yale University School of Medicine, New Haven, Connecticut; Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut; Clinical Epidemiology Research Center, VA-Connecticut Healthcare System, West Haven, Connecticut.
Chirag R Parikh
Guadalupe Garcia-Tsao

Funding

Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI MICHAEL H NATHANSON · 1986 to 2026
$31.1M
CIRRHOSIS AND ITS COMPLICATIONSK24DK002727 · NIDDK · YALE UNIVERSITY · PI GARCIA-TSAO, GUADALUPE · 1999 to 2009
$1.3M
Mentoring Program for Translational and Patient Oriented Research in AKIK24DK090203 · NIDDK · YALE UNIVERSITY · PI PARIKH, CHIRAG R · 2012 to 2016
$896k
NIDDK NIH HHS K24 DK002727NIDDK NIH HHS K24 DK090203NIDDK NIH HHS K24DK0902030NIDDK NIH HHS P30 DK034989
6 · The paper itself

Abstract

A 62-year-old man with cirrhosis secondary to hepatitis C and chronic alcohol abuse was admitted to the intensive care unit with hematemesis and mental status changes. Physical examination showed ascites and stigmata of chronic liver disease. Blood pressure was noted as 87/42 mm Hg and laboratory studies showed a serum creatinine level of 0.8 mg/dL, an estimated glomerular filtration rate of 84 mL/min/1.73 m(2) calculated using the Modification of Diet in Renal Disease Study equation, a serum sodium level of 123 mEq/L, a total serum bilirubin level of 4.3 mg/dL, and an international normalization ratio of 1.6. The patient was resuscitated with packed red blood cells and fresh-frozen plasma and bleeding was controlled. However, on the third day of admission, creatinine level increased to 1.5 mg/dL. Examination of urine sediment showed 1 to 5 bilirubin-stained granular casts per high-powered field and a few renal tubular epithelial cells. The urine sodium level was 21 mEq/L and the fractional excretion of sodium was 0.43%.

Indexed as

Acute Kidney InjuryAlcoholismBilirubinBiomarkersCreatinineHepatitis C, ChronicHumansLiver CirrhosisMaleMiddle AgedSodiumBilirubinBiomarkersCreatinineSodiumacute kidney injuryAcute Kidney Injury Networkacute tubular necrosisAcute Tubular NecrosisAKIAKINAscitesATNchronic kidney diseaseCirrhosisCKDFENafractional excretion of sodiumGFRglomerular filtration rateHepatorenalhepatorenal syndromeHRSIACICUintensive care unitInternational Ascites ClubKidney Injurykidney injury molecule-1KIM-1MDRDModification of Diet in Renal Diseaseneutrophil gelatinase–associated lipocalinNGALodds ratioORPRAprerenal azotemiaRAASrenin-angiotensin-aldosterone systemUrinary Biomarkers

Identifiers

PMID23583467
PMCPMC3840046

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.