SynthesisJournal of pediatric surgery2013
Primary fascial closure versus staged closure with silo in patients with gastroschisis: a meta-analysis.
Synthesis in Journal of pediatric surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03185637 (Paediatric Surgery Across Sub-Saharan Africa), which is not on this map. Cited by 40 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Paediatric Surgery Across Sub-Saharan Africa: A Multi-Centre Prospective Cohort Study
Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Avoidance of routine endotracheal intubation and general anesthesia for primary closure of gastroschisis: a systematic review and meta-analysis.Pediatric surgery international · 2022Pooled it
- Safety and usefulness of plastic closure in infants with gastroschisis: a systematic review and meta-analysis.Pediatric surgery international · 2019Pooled it
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- Variability of outcome reporting in Hirschsprung's Disease and gastroschisis: a systematic review.Scientific reports · 2016Pooled it
- Pooled it
- A Historical Review of Gastroschisis: Evolution of Understanding, Diagnosis, and Surgical Management.Children (Basel, Switzerland) · 2025Review
- Early versus delayed silo closure in gastroschisis: a retrospective study.Pediatric surgery international · 2025Article
- The outcomes of treatment between primary closure and staged closure in gastroschisis in the pre and post era of the bedside wound retractor silo placement technique.Pediatric surgery international · 2025Article
- Evaluation of the Management of Gastroschisis in Aristide Le Dantec University Hospital Center in Dakar: A Cross Sectional Study.African journal of paediatric surgery : AJPS · 2024Article
- Case Report: foetal gastroschisis with ideal pregnancy outcomes under multidisciplinary treatment management.Frontiers in pediatrics · 2024Article
- Gastroschisis in Sub-Saharan Africa: a scoping review of the prevalence, management practices, and associated outcomes.Pediatric surgery international · 2023Article
- Therapeutic Hypothermia Treatment for an Infant with Hypoxic-Ischemic Encephalopathy and Gastroschisis: A Case Report.AJP reports · 2023Article
- Predictors of length of stay for simple gastroschisis: analysis of ACS NSQIP-P database.Pediatric surgery international · 2022Article
- Improved Mortality of Patients with Gastroschisis: A Historical Literature Review of Advances in Surgery and Critical Care from 1960-2020.Children (Basel, Switzerland) · 2022Review
- Concomitant Hepatectomy and Atrial Thrombectomy under Cardiopulmonary Bypass versus Staged Hepatectomy in the Treatment for Hepatocellular Carcinoma with Large Right Atrial Tumor Thrombi.Journal of clinical medicine · 2022Article
- Gastroschisis: A Successful, Prospectively Evaluated Treatment Model in a Middle-Income Country.World journal of surgery · 2022Article
- Gastroschisis with intestinal atresia leads to longer hospitalization and poor feeding outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Different strategies, equivalent treatment approaches in terms of mortality in four university hospitals: a retrospective multicenter study of gastroschisis in Finland.Pediatric surgery international · 2021Article
- Is fetal magnetic resonance imaging volumetry of eventrated organs in gastroschisis predictive for surgical treatment?Pediatric radiology · 2021Article
- Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study.Lancet (London, England) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
background/purposeGastroschisis is the most common congenital abdominal wall defect. Despite advances in the surgical closure of gastroschisis, consensus is lacking as to which method results in the best patient outcomes. The purpose of this meta-analysis was to compare short-term outcomes associated with primary fascial closure and staged repair with a silo in patients with gastroschisis.
methodsWe reviewed Medline citations, as well as the Cochrane Database of Systematic Reviews, between January 1, 1996 and June 1, 2012. Articles were identified using the search term "gastroschisis" and [("treatment outcome" or "prognosis") or randomized controlled trials]. Case reports, reviews, letters, abstracts only, non-English abstracts, and studies that did not address at least one of the outcomes of interest were excluded from the meta-analysis. Two independent reviewers identified relevant articles for final inclusion. A standard data collection form created by the authors was used to extract study information, including study design, patient characteristics, and reported patient outcomes. The data were analyzed using standard meta-analytic techniques.
resultsTwenty studies were included in the meta-analysis. In the five studies that selected closure method randomly or as a temporal shift in practice, silo was associated with better outcomes, with a significant reduction in ventilator days (p<0.0001), time to first feed (p=0.04), and infection rates (p=0.03). When all studies were included, primary closure was associated with improved outcomes.
conclusionsSilo closure is associated with better clinical outcomes in the studies with the least selection bias. Larger prospective studies are needed to definitively determine the best closure technique.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.