Evidence map›Paper›PMID 23582967›Full record

ReviewSeminars in perinatology2013

Pulmonary hypertension in bronchopulmonary dysplasia.

Sara K Berkelhamer, Karen K Mestan, Robin H Steinhorn

Abstract readReview
In one paragraph

Review in Seminars in perinatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 1 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 1 synthesis or guideline pooled it, 174 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Right ventricle speckle tracking in bronchopulmonary dysplasia: one-year follow-up.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sara K BerkelhamerNorthwestern University Feinberg School of Medicine, Chicago, IL, USA.
Karen K Mestan
Robin H Steinhorn
Northwestern University · USUC Davis Children's Hospital · US

Funding

REDOX REGULATION IN THE PERINATAL PULMONARY VASCULATURER01HL054705 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI STEINHORN, ROBIN H. · 2001 to 2013
$4.8M
Oxidant Stress and Gene Polymorphisms in Bronchopulmonary DysplasiaK23HL093302 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI MESTAN, KAREN K · 2010 to 2013
$538k
CGMP REGULATION IN THE DEVELOPING PULMONARY VASCULATURER29HL054705 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI STEINHORN, ROBIN H · 1995 to 1998
–
NHLBI NIH HHS HL093302NHLBI NIH HHS HL54705NHLBI NIH HHS K23 HL093302NHLBI NIH HHS R01 HL054705NHLBI NIH HHS R29 HL054705
6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a common complication of neonatal respiratory diseases, including bronchopulmonary dysplasia (BPD), and recent studies have increased awareness that PH worsens the clinical course, morbidity and mortality of BPD. Recent evidence indicates that up to 18% of all extremely low-birth-weight infants will develop some degree of PH during their hospitalization, and the incidence rises to 25-40% of the infants with established BPD. Risk factors are not yet well understood, but new evidence shows that fetal growth restriction is a significant predictor of PH. Echocardiography remains the primary method for evaluation of BPD-associated PH, and the development of standardized screening timelines and techniques for identification of infants with BPD-associated PH remains an important ongoing topic of investigation. The use of pulmonary vasodilator medications, such as nitric oxide, sildenafil, and others, in the BPD population is steadily growing, but additional studies are needed regarding their long-term safety and efficacy.

Indexed as

Bronchopulmonary DysplasiaEchocardiographyHumansHypertension, PulmonaryInfant, NewbornInfant, PrematureVasodilator AgentsVasodilator Agents

Identifiers

PMID23582967
PMCPMC4464837
OpenAlexW1983737745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.