ArticleAntioxidants & redox signaling2014
Production and physiological effects of hydrogen sulfide.
Article in Antioxidants & redox signaling, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
162 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Donor Heart Preservation with Hydrogen Sulfide: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2021Pooled it
- Significance of GSH and HRedox report : communications in free radical research · 2026Review
- 1,8-Naphthalimide: A Versatile Platform for the Design of Fluorescent Probes Targeting Hydrogen Sulfide in Biological Systems.Molecules (Basel, Switzerland) · 2026Review
- The Effect of Hydrogen Sulfide and Reactive Sulfur Species on Bacterial Virulence and Antibiotic Sensitivity.International journal of molecular sciences · 2026Review
- Quorum-sensing regulator LsrR modulates resistance to oxidative stress by interfering with sulfate assimilation in avian pathogenicJournal of bacteriology · 2026Article
- Targeted HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hydrogen sulfide alleviates hyperoxia effects on mitochondria in human developing airway smooth muscle.JCI insight · 2026Article
- Dual-organelle localizing fluorescent probe for selective hydrogen sulfide imaging in mitochondria and lysosomes.Analytical and bioanalytical chemistry · 2025Article
- Role of cystathionine-β-synthase and hydrogen sulfide in down syndrome.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Unveiling Hydrogen Sulfide: A New Frontier in Neuroprotection and Neuromodulation.Indian journal of clinical biochemistry : IJCB · 2025Review
- Ammonium depletion induces changes in low molecular weight thiol levels in Escherichia coli and Bacillus subtilis.Archives of microbiology · 2025Article
- Hydrogen Sulfide (HInternational journal of molecular sciences · 2025Review
- The Janus Face of Oxidative Stress and Hydrogen Sulfide: Insights into Neurodegenerative Disease Pathogenesis.Antioxidants (Basel, Switzerland) · 2025Review
- Article
- The Pivotal Role of One-Carbon Metabolism in Neoplastic Progression During the Aging Process.Biomolecules · 2024Review
- Stress-Induced Sulfide Production byMicroorganisms · 2024Article
- Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids.Antioxidants (Basel, Switzerland) · 2024Article
- Exploring the Mechanism of HInternational journal of molecular sciences · 2024Article
- The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species.Chemico-biological interactions · 2024Article
- Electrochemical Detection of Gasotransmitters: Status and Roadmap.ACS sensors · 2024Review
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
significanceHydrogen sulfide (H2S) has been recognized as a physiological mediator with a variety of functions. It regulates synaptic transmission, vascular tone, inflammation, transcription, and angiogenesis; protects cells from oxidative stress and ischemia-reperfusion injury; and promotes healing of ulcers. RECENT ADVANCES: In addition to cystathionine β-synthase and cystathionine γ-lyase, 3-mercaptopyruvate sulfurtransferase along with cysteine aminotransferase was recently demonstrated to produce H2S. Even in bacteria, H2S produced by these enzymes functions as a defense against antibiotics, suggesting that the cytoprotective effect of H2S is a universal defense mechanism in organisms from bacteria to mammals. CRITICAL ISSUES: The functional form of H2S-undissociated H2S gas, dissociated HS ion, or some other form of sulfur-has not been identified. FUTURE DIRECTIONS: The regulation of H2S production by three enzymes may lead to the identification of the physiological signals that are required to release H2S. The identification of the physiological functions of other forms of sulfur may also help understand the biological significance of H2S.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.