Evidence map›Paper›PMID 23581912›Full record

ArticleJournal of the American Geriatrics Society2013

When comorbidity, aging, and complexity of primary care meet: development and validation of the Geriatric CompleXity of Care Index.

Lillian Min, Neil Wenger, Anne M Walling, Caroline Blaum, Christine Cigolle, David A Ganz, David Reuben, Paul Shekelle, Carol Roth, Eve A Kerr

Abstract readValidation Study
In one paragraph

Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pilot study on the use of a multimorbidity index in patients receiving home parenteral nutrition.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lillian MinDivision of Geriatrics, Department of Medicine, School of Medicine, University of Michigan, Ann Arbor, MI 48109, USA. lmin@med.umich.edu
Neil Wenger
Anne M Walling
Caroline Blaum
Christine Cigolle
David A Ganz
David Reuben
Paul Shekelle
Carol Roth
Eve A Kerr

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Geriatric Conditions and Disablement in the Older Adult PopulationK08AG031837 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CIGOLLE, CHRISTINE T · 2010 to 2014
$639k
Prioritizing Care of Complex Elders using Survival and Functional Status OutcomesR21HS017621 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MIN, LILLIAN CHIANG · 2008 to 2009
$263k
AHRQ HHS R21 HS017621NIA NIH HHS K08 AG031837NIA NIH HHS P30 AG024824NIDDK NIH HHS P30 DK092926
6 · The paper itself

Abstract

objectivesTo develop and validate the Geriatric CompleXity of Care Index (GXI), a comorbidity index of medical, geriatric, and psychosocial conditions that addresses disease severity and intensity of ambulatory care for older adults with chronic conditions.

designDEVELOPMENT phase: variable selection and rating by clinician panel. VALIDATION phase: medical record review and secondary data analysis.

settingAssessing the Care of Vulnerable Elders-2 study.

participantsSix hundred forty-four older (≥75) individuals receiving ambulatory care. MEASURES: DEVELOPMENT: 32 conditions categorized according to severity, resulting in 117 GXI variables. A panel of clinicians rated each GXI variable with respect to the added difficulty of providing primary care for an individual with that condition. VALIDATION: Modified versions of previously validated comorbidity measures (simple count, Charlson, Medicare Hierarchical Condition Category), longitudinal clinical outcomes (functional decline, survival), intensity of ambulatory care (primary, specialty care visits, polypharmacy, number of eligible quality indicators (NQI)) over 1 year of care.

resultsThe most-morbid individuals (according to quintiles of GXI) had more visits (7.0 vs 3.7 primary care, 6.2 vs 2.4 specialist), polypharmacy (14.3% vs 0% had ≥14 medications), and greater NQI (33 vs 25) than the least-morbid individuals. Of the four comorbidity measures, the GXI was the strongest predictor of primary care visits, polypharmacy, and NQI (P < .001, controlling for age, sex, function-based vulnerability).

conclusionOlder adults with complex care needs, as measured by the GXI, have healthcare needs above what previously employed comorbidity measures captured. Healthcare systems could use the GXI to identify the most complex elderly adults and appropriately reimburse primary providers caring for older adults with the most complex care needs for providing additional visits and coordination of care.

Indexed as

Health Status IndicatorsSeverity of Illness IndexAgedAged, 80 and overAgingChronic DiseaseComorbidityFemaleGeriatric AssessmentHealth Services for the AgedHealth Services ResearchHumansMalePrimary Health CareQuality Assurance, Health Care

Identifiers

PMID23581912
PMCPMC3698956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.