ArticleJournal of experimental botany2013
Low temperatures induce rapid changes in chromatin state and transcript levels of the cereal VERNALIZATION1 gene.
Article in Journal of experimental botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 90 citations in OpenAlex.
- Temperature regulation in plants: From molecular mechanisms to climate-resilient crop improvement.Journal of integrative plant biology · 2026Review
- Optimizing wheat development to a range of winter climates.Journal of experimental botany · 2026Review
- Molecular-physiological model integration revolutionizes cereal flowering prediction.The New phytologist · 2026Article
- O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering.Nature communications · 2025Article
- Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat.Genome biology · 2024Article
- Cytoplasm of the Wild SpeciesPlants (Basel, Switzerland) · 2024Article
- Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat.Science China. Life sciences · 2024Article
- Epigenomic identification of vernalization cis-regulatory elements in winter wheat.Genome biology · 2024Article
- A molecular mechanism for embryonic resetting of winter memory and restoration of winter annual growth habit in wheat.Nature plants · 2024Article
- Dynamics of apex and leaf development in barley as affected byFrontiers in plant science · 2024Article
- Wheat genomic study for genetic improvement of traits in China.Science China. Life sciences · 2022Review
- Flowering time runs hot and cold.Plant physiology · 2022Review
- Advancing understanding of oat phenology for crop adaptation.Frontiers in plant science · 2022Review
- Hybrids Provide More Options for Fine-Tuning Flowering Time Responses of Winter Barley.Frontiers in plant science · 2022Article
- Temporal expression study of miRNAs in the crown tissues of winter wheat grown under natural growth conditions.BMC genomics · 2021Article
- Major flowering time genes of barley: allelic diversity, effects, and comparison with wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Transcriptional memories mediate the plasticity of cold stress responses to enable morphological acclimation in Brachypodium distachyon.The New phytologist · 2021Article
- Responses of Barley to High Ambient Temperature Are Modulated by Vernalization.Frontiers in plant science · 2021Article
- Understanding Past, and Predicting Future, Niche Transitions based on Grass Flowering Time Variation.Plant physiology · 2020Review
- Evidence for the Involvement of Vernalization-related Genes in the Regulation of Cold-induced Ripening in 'D'Anjou' and 'Bartlett' Pear Fruit.Scientific reports · 2020Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcriptional activation of the VERNALIZATION1 gene mediates the acceleration of flowering by prolonged cold (vernalization) in temperate cereals. This study examined the earliest stages of the transcriptional response of VRN1 to low temperatures. Time-course analyses, using a sensitive quantitative PCR assay, showed that in sprouting barley seedlings VRN1 transcripts begin to accumulate within 24 hours of the onset of cold. The kinetics of the initial transcriptional response of VRN1 to cold was similar to the cold-induced genes DEHYDRIN5 (DHN5) and COLD REGULATED 14B (COR14B), but occurred at lower levels compared to cold acclimation genes or the response to longer cold treatments. Temperatures between 15 and -2 °C induced expression of VRN1 within 24 hours, with a maximal response observed between 2 and -2 °C. Transcriptional induction was also observed in undifferentiated callus cells. There were significant increases in histone acetylation levels at the VRN1 locus in response to 24-hour cold treatment. Sodium butyrate, a histone deacetylation inhibitor, triggered an increase in histone acetylation at VRN1 chromatin and elevated VRN1 transcript levels. The transcriptional response of VRN1 to short-term cold treatment was examined in near-isogenic lines that have different VRN1 genotypes, showing that an allele of the barley VRN1 gene with an insertion in the first intron and high basal expression levels has a reduced transcriptional response to short term cold treatment. This study suggests that low-temperature induction of VRN1 is a cellular response to cold triggered by the same mechanisms that mediate low-temperature induction of cold acclimation genes.
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