Evidence map›Paper›PMID 23580329›Full record

ReviewFrontiers in neural circuits2013

The role of zebrafish (Danio rerio) in dissecting the genetics and neural circuits of executive function.

Matthew O Parker, Alistair J Brock, Robert T Walton, Caroline H Brennan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neural circuits, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 131 citations in OpenAlex.

  1. Article
  2. Zebrafish frk Gene Knockout Shows Social Impairments Relevant to Autism and Delays Brain Development by Increasing Cell Proliferation.Autism research : official journal of the International Society for Autism Research · 2026
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  15. iScience · 2023
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew O ParkerSchool of Biological and Chemical Sciences, Queen Mary University of London London, UK.
Alistair J Brock
Robert T Walton
Caroline H Brennan
Queen Mary University of London · GB

Funding

Department of Health RP-PG-0609-10181Medical Research Council MC_U190081977National Centre for the Replacement, Refinement and Reduction of Animals in Research G1000053/1
6 · The paper itself

Abstract

Zebrafish have great potential to contribute to our understanding of behavioral genetics and thus to contribute to our understanding of the etiology of psychiatric disease. However, progress is dependent upon the rate at which behavioral assays addressing complex behavioral phenotypes are designed, reported and validated. Here we critically review existing behavioral assays with particular focus on the use of adult zebrafish to explore executive processes and phenotypes associated with human psychiatric disease. We outline the case for using zebrafish as models to study impulse control and attention, discussing the validity of applying extant rodent assays to zebrafish and evidence for the conservation of relevant neural circuits.

Indexed as

AnimalsAttentionExecutive FunctionHumansLearningNerve NetZebrafishattentionbehavioral flexibilityimpulsivityneural circuitspsychiatric disorderzebrafish

Identifiers

PMID23580329
PMCPMC3619107
OpenAlexW2094740113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.