ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2013
Different value of coronary calcium score to predict obstructive coronary artery disease in patients with and without moderate chronic kidney disease.
Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Loss of nighttime blood pressure dipping as a risk factor for coronary artery calcification in nondialysis chronic kidney disease.Medicine · 2017Trial
- Correlation Between Coronary Artery Disease Severity Detected by CT Coronary Angiography and Grade of Left Ventricular Diastolic Dysfunction Detected by Echocardiography.Journal of clinical medicine · 2025Article
- Coronary artery calcification score as the determinant of coronary artery disease in chronic kidney disease patients: A preliminary study.ARYA atherosclerosis · 2024Article
- Vascular Calcification in Chronic Kidney Disease: Distinct Features of Pathogenesis and Clinical Implication.Korean circulation journal · 2021Review
- Preoperative Cardiovascular Assessment of the Renal Transplant Recipient: A Narrative Review.Journal of clinical medicine · 2021Review
- The Clinical Value of Klotho and FGF23 in Cardiac Valve Calcification Among Patients with Chronic Kidney Disease.International journal of general medicine · 2021Article
- Extracellular Fluid Excess Is Significantly Associated With Coronary Artery Calcification in Patients With Chronic Kidney Disease.Journal of the American Heart Association · 2018Observational
- Correlation of coronary plaque characteristics and obstructive stenosis with chronic kidney disease by coronary CT angiography.Cardiovascular diagnosis and therapy · 2015Article
- The PROMISE study: a clear promise for functional stress testing in patients with suspected coronary artery disease.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2015Article
- Screening in asymptomatic coronary artery disease: helpful, redundant or harmful?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2014Article
- Role of computed tomography for diagnosis and risk stratification of patients with suspected or known coronary artery disease.Arteriosclerosis, thrombosis, and vascular biology · 2014Review
- Does hybrid imaging have a role in cardiac risk evaluation of the pre-renal transplant patient?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Coronary artery calcification: does it predict obstructive coronary artery disease?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2013Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe coronary calcium score (CCS) predicts significant coronary artery disease (CAD) in the general population. While moderate chronic kidney disease (CKD) is associated with high CCS, the use of CCS to predict significant CAD in these patients is unknown.
methodsA total of 704 patients underwent computed tomography coronary angiography for the assessment of CCS and CAD. Sixty-nine (10 %) patients had moderate CKD, defined by an estimated glomerular filtration rate (eGFR) between 30 and 59 mL/min/1.73m(2), and the remaining patients were considered to be without significant CKD (eGFR ≥ 60 mL/min/1.73m(2)).
resultsPatients with moderate CKD were older, had a higher CCS, and a higher prevalence of obstructive CAD than patients without significant CKD. Receiver-operator curve analysis showed that CCS predicted the presence of obstructive CAD in both patients with moderate CKD and those without significant CKD. In patients with moderate CKD, the optimal cut-off value of CCS to diagnose obstructive CAD was 140 (sensitivity 73 % and specificity of 70 %), and is 2.8 fold higher than in patients without significant CKD (cut-off value = 50; sensitivity 75 % and specificity 75 %).
conclusionThe present results demonstrate that CCS can predict obstructive CAD in patients with moderate CKD, although the optimal cut-off value is higher than in patients without significant CKD.
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Registered trials
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