Evidence map›Paper›PMID 23579780›Full record

ArticleNature protocols2013

Collecting, rearing, spawning and inducing regeneration of the starlet sea anemone, Nematostella vectensis.

Derek J Stefanik, Lauren E Friedman, John R Finnerty

Abstract read
PubMed Publisher
In one paragraph

Article in Nature protocols, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 91 citations in OpenAlex.

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  10. Hypoxia disrupts metabolism in coral and sea anemone larvae.The Journal of experimental biology · 2025
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  20. The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemoneProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Derek J StefanikDepartment of Biology, Boston University, Boston, Massachusetts, USA.
Lauren E Friedman
John R Finnerty
Boston University · US

Funding

A functional systems biology approach to investigating the role of Wnt/beta-catenF31GM095289 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI STEFANIK, DEREK JOHN · 2011 to 2013
$88k
NIGMS NIH HHS F31 GM095289-01
6 · The paper itself

Abstract

Over the past 20 years, the starlet sea anemone, Nematostella vectensis, a small estuarine animal, has emerged as a powerful model system for field and laboratory studies of development, evolution, genomics, molecular biology and toxicology. Here we describe how to collect Nematostella, culture it through its entire sexual life cycle and induce regeneration for the production of clonal stocks. In less than 1 h at a suitable field site, a researcher on foot can collect hundreds of individual anemones. In a few months, it is possible to establish a laboratory colony that will be reliable in generating hundreds or thousands of fertilized eggs on a roughly weekly schedule. By inducing regeneration roughly every 2 weeks, in less than 6 months, one can establish a clonal stock consisting of hundreds of genetically identical anemones. These results can be achieved very inexpensively and without specialized equipment.

Indexed as

RegenerationAnimalsLaboratory Animal ScienceLife Cycle StagesModels, BiologicalPhotoperiodReproductionSea AnemonesSeawaterTemperature

Identifiers

PMID23579780
OpenAlexW2063202985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.