ArticleFrontiers in computational neuroscience2013
Neural bases of hand synergies.
Article in Frontiers in computational neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03034785 (Young Hands at Work and Play), which is not on this map. Cited by 99 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Young Hands at Work and Play: Flexible Electronics for Early Assessment of Force Modulation and Planning in Children Born Prematurely
Who cites it
99 citing papers in PubMed, 1 synthesis or guideline pooled it, 251 citations in OpenAlex.
- A Systematic Review of EMG Applications for the Characterization of Forearm and Hand Muscle Activity during Activities of Daily Living: Results, Challenges, and Open Issues.Sensors (Basel, Switzerland) · 2021Pooled it
- Sensing and decoding the neural drive to paralyzed muscles during attempted movements of a person with tetraplegia using a sleeve array.Journal of neurophysiology · 2021Trial
- Changes in peripheral sensory afference do not alter predictive motor planning: evidence from carpal tunnel syndrome.Experimental brain research · 2026Article
- Characterization of Muscle Synergies During Activities of Daily Living Using Surface EMG: A Functional Reference for Neuromuscular Assessment.Journal of clinical medicine · 2026Article
- Early skill learning is shaped by the offline emergence of expert synergies.Current biology : CB · 2026Article
- Superficial Ventral Premotor Pathways to Primary Motor Cortex Shape the Temporal Coordination of Precision Graspinnog.The European journal of neuroscience · 2026Article
- Coordinated hand movement sensation revealed through an implanted magnetic prosthetic kinesthetic interface.Science advances · 2026Article
- Flexible Perception of Tactile Cues in Multiple Reference Frames.bioRxiv : the preprint server for biology · 2026Article
- Effect of slit-regulated 3D embroidered sensor structures on contact area-variation-based strain sensing performance in smart gloves.Scientific reports · 2026Article
- Expert Motor Synergies Emerge Predominantly Offline During Early Skill Learning.bioRxiv : the preprint server for biology · 2026Article
- Manual Dexterity Rehabilitation in Parkinson's Disease and Paranoid Schizophrenia: A Controlled Study.Life (Basel, Switzerland) · 2026Article
- A single low-dimensional neural component of spinal motor neuron activity explains force generation across repetitive isometric tasks.iScience · 2025Article
- Neuromuscular control of a five-finger pinch task is influenced by training history.Experimental brain research · 2025Article
- Object-directed action representations are componentially built in parietal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Carpal tunnel release surgery restores force control but not force coordination in CTS patients.Scientific reports · 2025Article
- Explaining human motor coordination via the synergy expansion hypothesis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Spatial and spectral changes in cortical surface potentials during pinching versusthumb and index finger flexion.Neuroscience letters · 2025Article
- Hypergravity is more challenging than microgravity for the human sensorimotor system.NPJ microgravity · 2025Article
- Neural control meets biomechanics in the motor assessment of neurological disorders: a narrative review.Frontiers in neural circuits · 2025Review
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
The human hand has so many degrees of freedom that it may seem impossible to control. A potential solution to this problem is "synergy control" which combines dimensionality reduction with great flexibility. With applicability to a wide range of tasks, this has become a very popular concept. In this review, we describe the evolution of the modern concept using studies of kinematic and force synergies in human hand control, neurophysiology of cortical and spinal neurons, and electromyographic (EMG) activity of hand muscles. We go beyond the often purely descriptive usage of synergy by reviewing the organization of the underlying neuronal circuitry in order to propose mechanistic explanations for various observed synergy phenomena. Finally, we propose a theoretical framework to reconcile important and still debated concepts such as the definitions of "fixed" vs. "flexible" synergies and mechanisms underlying the combination of synergies for hand control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.