Evidence map›Paper›PMID 23579206›Full record

ArticleNanotechnology2013

An electro-hydrodynamics-based model for the ionic conductivity of solid-state nanopores during DNA translocation.

Binquan Luan, Gustavo Stolovitzky

Abstract read
In one paragraph

Article in Nanotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Binquan LuanIBM Research, 1101 Kitchawan Road, Yorktown Heights, NY 10598, USA.
Gustavo Stolovitzky

Funding

Nanopore-based Electrical Device for DNA SequencingR01HG005110 · NHGRI · IBM THOMAS J. WATSON RESEARCH CENTER · PI STOLOVITZKY, GUSTAVO ALEJANDRO · 2009 to 2011
$2.5M
NHGRI NIH HHS R01 HG005110NHGRI NIH HHS R01-HG05110-01
6 · The paper itself

Abstract

A solid-state nanopore can be used to sense DNA (or other macromolecules) by monitoring ion-current changes that result from translocation of the molecule through the pore. When transiting a nanopore, the highly negatively charged DNA interacts with a nanopore both electrically and hydrodynamically, causing a current blockage or a current enhancement at different ion concentrations. This effect was previously characterized using a phenomenological model that can be considered as the limit of the electro-hydrodynamics model presented here. We show theoretically that the effect of surface charge of a nanopore (or electro-osmotic effect) can be equivalently treated as modifications of electrophoretic mobilities of ions in the pore, providing an improved physical understanding of the current blockage (or enhancement).

Indexed as

NanoporesDNAElectricityHydrodynamicsIonsModels, ChemicalOsmosisStatic ElectricityDNAIons

Identifiers

PMID23579206
PMCPMC3681960

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.