ArticleGynecologic oncology2013
Multiple large bowel resections: potential risk factor for anastomotic leak.
Article in Gynecologic oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Protective ostomies in ovarian cancer surgery: a systematic review and meta-analysis.Journal of gynecologic oncology · 2022Pooled it
- Survival impact of bowel resection at the time of interval cytoreductive surgery for advanced ovarian cancer: a retrospective cohort study using inverse probability of treatment weighting.World journal of surgical oncology · 2026Article
- Article
- Review
- Anastomotic leakage after resection of the rectosigmoid colon in primary ovarian cancer.Journal of ovarian research · 2023Article
- Application and evaluation of transitory protective stoma in ovarian cancer surgery.Frontiers in oncology · 2023Review
- Anastomotic Leakage after Colorectal Surgery in Ovarian Cancer: Drainage, Stoma Utility and Risk Factors.Cancers · 2022Article
- [Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in ovarian cancer].Chirurgie (Heidelberg, Germany) · 2022Review
- Anastomotic Leak in Ovarian Cancer Cytoreduction Surgery: A Systematic Review and Meta-Analysis.Cancers · 2022Review
- Risk Factors for Anastomotic Leakage in Advanced Ovarian Cancer Surgery: A Large Single-Center Experience.Annals of surgical oncology · 2022Article
- The surgical outcomes and perioperative complications of bowel resection as part of debulking surgery of advanced ovarian cancer patients.BMC surgery · 2022Article
- Survival impact of bowel resection at the time of interval cytoreductive surgery for advanced ovarian cancer.Gynecologic oncology reports · 2021Article
- Article
- Surgical technique of visceral segmental serosectomy for advanced ovarian cancer.Gland surgery · 2021Article
- Clinical Phenotypes of Tumors Invading the Rectosigmoid Colon Affecting the Extent of Debulking Surgery and Survival in Advanced Ovarian Cancer.Frontiers in oncology · 2021Article
- Postoperative Intestinal Fistula in Primary Advanced Ovarian Cancer Surgery.Cancer management and research · 2021Article
- Upfront debulking surgery for high-grade serous ovarian carcinoma: current evidence.Annals of translational medicine · 2020Review
- Bowel resection rate but not bowel related morbidity is decreased after interval debulking surgery compared to primary surgery in patents with stage IIIC-IV ovarian cancer.Journal of gynecologic oncology · 2019Article
- Outcome of Bowel Resection in Women with Advanced Ovarian Carcinoma.Indian journal of surgical oncology · 2018Article
- A Comparison of Thermal Plasma Energy Versus Argon Beam Coagulator-Induced Intestinal Injury After Vaporization in a Porcine Model.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesIdentify risk factors of anastomotic leak (AL) after large bowel resection (LBR) for ovarian cancer (OC) and compare outcomes between AL and no AL.
methodsAll cases of AL after LBR for OC between 01/01/1994 and 05/20/2011 were identified and matched 1:2 with controls for age (±5 years), sub-stage (IIIA/IIIB; IIIC; IV), and date of surgery (±4 years). Patient-specific and intraoperative risk factors, use of protective stomas, and outcomes were abstracted. A stratified conditional logistic regression model was fit to determine the association between each factor and AL.
results42 AL cases were evaluable and matched with 84 controls. Two-thirds of the AL had stage IIIC disease and >90% of both cases and controls were cytoreduced to <1cm residual disease. No patient-specific risk factors were associated with AL (pre-operative albumin was not available for most patients). Rectosigmoid resection coupled with additional LBR was associated with AL (OR=2.73, 95% CI 1.13-6.59, P=0.025), and protective stomas were associated with decreased risk of AL (0% vs. 10.7%, P=0.024). AL patients had longer length of stay (P<0.001), were less likely to start chemotherapy (P=0.020), and had longer time to chemotherapy (P=0.007). Cases tended to have higher 90-day mortality (P=0.061) and were more likely to have poorer overall survival (HR=2.05, 95% CI 1.18-3.57, P=0.011).
conclusionsMultiple LBRs appear to be associated with increased risk of AL and protective stomas with decreased risk. Since AL after OC cytoreduction significantly delays chemotherapy and negatively impacts survival, surgeons should strongly consider temporary diversion in selected patients (poor nutritional status, multiple LBRs, previous pelvic radiation, very low anterior resection, steroid use).
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