ReviewAnnual review of analytical chemistry (Palo Alto, Calif.)2013
Structure determination of membrane proteins by nuclear magnetic resonance spectroscopy.
Review in Annual review of analytical chemistry (Palo Alto, Calif.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Recent Advances in Detergent Chemistry and Handling Support Membrane Protein Analysis Including Lipid Interactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Detergent-free isolation and characterization of amyloid precursor protein C99 in E. coli native lipid-nanodiscs using non-ionic polymer.Protein science : a publication of the Protein Society · 2025Article
- Regulatory Guidelines for the Analysis of Therapeutic Peptides and Proteins.Journal of peptide science : an official publication of the European Peptide Society · 2025Review
- Identifying potential drug-target interactions based on ensemble deep learning.Frontiers in aging neuroscience · 2023Article
- Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics.Scientific reports · 2022Article
- Spectroscopic signatures of bilayer ordering in native biological membranes.Biochimica et biophysica acta. Biomembranes · 2022Article
- Chemogenomic Approaches for Revealing Drug Target Interactions in Drug Discovery.Current genomics · 2021Review
- Current Approaches in Supersecondary Structures Investigation.International journal of molecular sciences · 2021Review
- AutoDTI++: deep unsupervised learning for DTI prediction by autoencoders.BMC bioinformatics · 2021Article
- A comparative chemogenic analysis for predicting Drug-Target Pair via Machine Learning Approaches.Scientific reports · 2020Article
- COACH-D: improved protein-ligand binding sites prediction with refined ligand-binding poses through molecular docking.Nucleic acids research · 2018Article
- Concentration-dependent changes to diffusion and chemical shift of internal standard molecules in aqueous and micellar solutions.Journal of biomolecular NMR · 2018Article
- Engineered Cross-Linking to Study the Pore Architecture of the CRAC Channel.Methods in molecular biology (Clifton, N.J.) · 2018Article
- Preserved Transmembrane Segment Topology, Structure, and Dynamics in Disparate Micellar Environments.The journal of physical chemistry letters · 2017Article
- Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy.Angewandte Chemie (International ed. in English) · 2015Review
- In situ structural studies of Anabaena sensory rhodopsin in the E. coli membrane.Biophysical journal · 2015Article
- Structural studies of proteins by paramagnetic solid-state NMR spectroscopy.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2015Article
- Correlating lipid bilayer fluidity with sensitivity and resolution of polytopic membrane protein spectra by solid-state NMR spectroscopy.Biochimica et biophysica acta · 2015Article
- Membrane protein structure from rotational diffusion.Biochimica et biophysica acta · 2015Review
- Article
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Authors and funding
1 author.
Funding
Abstract
Many biological membranes consist of 50% or more (by weight) membrane proteins, which constitute approximately one-third of all proteins expressed in biological organisms. Helical membrane proteins function as receptors, enzymes, and transporters, among other unique cellular roles. Additionally, most drugs have membrane proteins as their receptors, notably the superfamily of G protein-coupled receptors with seven transmembrane helices. Determining the structures of membrane proteins is a daunting task because of the effects of the membrane environment; specifically, it has been difficult to combine biologically compatible environments with the requirements for the established methods of structure determination. There is strong motivation to determine the structures in their native phospholipid bilayer environment so that perturbations from nonnatural lipids and phases do not have to be taken into account. At present, the only method that can work with proteins in liquid crystalline phospholipid bilayers is solid-state NMR spectroscopy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.