ArticleISRN neurology2013
The human frontal lobes and frontal network systems: an evolutionary, clinical, and treatment perspective.
Article in ISRN neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuropsychological outcomes in patients with ruptured anterior communicating artery aneurysms treated by clipping versus coiling: a systematic review and meta-analysis.Neurosurgical review · 2024Pooled it
- Hippocampal radiotherapy dose constraints for predicting long-term neurocognitive outcomes: mature data from a prospective trial in young patients with brain tumors.Neuro-oncology · 2020Trial
- Potential neurophysiological mechanisms of intermittent theta-burst stimulation to the left prefrontal cortex for post-stroke unilateral neglect: An exploratory transcranial magnetic stimulation - electroencephalography study.IBRO neuroscience reports · 2025Article
- Are Oligodendrocytes the Culprits or Victims in Alzheimer's Disease.Physiological research · 2025Review
- Structure focused neurodegeneration convolutional neural network for modelling and classification of Alzheimer's disease.Scientific reports · 2024Article
- Examining longitudinal associations between prenatal exposure to infections and child brain morphology.Brain, behavior, and immunity · 2024Article
- Cortical grey matter volume differences in children with developmental coordination disorder compared to typically developing children.Frontiers in human neuroscience · 2024Article
- A case of spontaneous intracranial hypotension in a 45-year-old male with headache, behavior changes and altered mental status.Radiology case reports · 2022Article
- Can we rewire criminal mind via non-invasive brain stimulation of prefrontal cortex? Insights from clinical, forensic and social cognition studies.Current psychology (New Brunswick, N.J.) · 2022Article
- Lesions in different prefrontal sectors are associated with different types of acquired personality disturbances.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Observational
- Cognitive Impairment in People with Epilepsy.Journal of clinical medicine · 2022Review
- High Blood Lead Levels: An Increased Risk for Development of Brain Hyperintensities among Type 2 Diabetes Mellitus Patients.Biological trace element research · 2021Article
- Neuroimaging in infants with prenatal opioid exposure: Current evidence, recent developments and targets for future research.Journal of neuroradiology = Journal de neuroradiologie · 2021Review
- Brain Energy Metabolism in Two States of Mind Measured by Phosphorous Magnetic Resonance Spectroscopy.Frontiers in human neuroscience · 2021Article
- Value of the Frontal Assessment Battery Tool for Assessing the Frontal Lobe Function in Stroke Patients.Annals of rehabilitation medicine · 2020Article
- Plastic frontal pole cortex structure related to individual persistence for goal achievement.Communications biology · 2020Article
- Associations Between Altered Cerebral Activity Patterns and Psychosocial Disorders in Patients With Psychogenic Erectile Dysfunction: A Mediation Analysis of fMRI.Frontiers in psychiatry · 2020Article
- Pathways of Prevention: A Scoping Review of Dietary and Exercise Interventions for Neurocognition.Brain plasticity (Amsterdam, Netherlands) · 2019Article
- Neuro-hormonal Regulation Is a Better Indicator of Human Cognitive Abilities Than Brain Anatomy: The Need for a New Paradigm.Frontiers in neuroanatomy · 2019Article
- Frontal lobe syndrome associated with intracranial hemorrhages.International journal of legal medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frontal lobe syndromes, better termed as frontal network systems, are relatively unique in that they may manifest from almost any brain region, due to their widespread connectivity. The understandings of the manifold expressions seen clinically are helped by considering evolutionary origins, the contribution of the state-dependent ascending monoaminergic neurotransmitter systems, and cerebral connectivity. Hence, the so-called networktopathies may be a better term for the syndromes encountered clinically. An increasing array of metric tests are becoming available that complement that long standing history of qualitative bedside assessments pioneered by Alexander Luria, for example. An understanding of the vast panoply of frontal systems' syndromes has been pivotal in understanding and diagnosing the most common dementia syndrome under the age of 60, for example, frontotemporal lobe degeneration. New treatment options are also progressively becoming available, with recent evidence of dopaminergic augmentation, for example, being helpful in traumatic brain injury. The latter include not only psychopharmacological options but also device-based therapies including mirror visual feedback therapy.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.