ArticleFrontiers in plant science2013
Interaction of PLS and PIN and hormonal crosstalk in Arabidopsis root development.
Article in Frontiers in plant science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 65 citations in OpenAlex.
- Peptide hormones in shaping root system architecture and environmental adaptation: Current advances and translational perspectives.Plant communications · 2026Review
- POLARIS is a copper-binding peptide that interacts with ETR1 to negatively regulate ethylene signaling in Arabidopsis.Plant communications · 2025Article
- The Constrained Disorder Principle Overcomes the Challenges of Methods for Assessing Uncertainty in Biological Systems.Journal of personalized medicine · 2024Review
- A predictive model for ethylene-mediated auxin and cytokinin patterning in the Arabidopsis root.Plant communications · 2024Article
- Review
- Small open reading frames in plant research: from prediction to functional characterization.3 Biotech · 2022Review
- Plant Antimicrobial Peptides: State of the Art, In Silico Prediction and Perspectives in the Omics Era.Bioinformatics and biology insights · 2020Review
- Micropeptide.PLoS genetics · 2018Review
- Epidermal expression of a sterol biosynthesis gene regulates root growth by a non-cell-autonomous mechanism inDevelopment (Cambridge, England) · 2018Article
- Bayesian uncertainty analysis for complex systems biology models: emulation, global parameter searches and evaluation of gene functions.BMC systems biology · 2018Article
- Review
- Exogenous gibberellin enhances secondary xylem development and lignification in carrot taproot.Protoplasma · 2017Article
- A recovery principle provides insight into auxin pattern control in the Arabidopsis root.Scientific reports · 2017Article
- Abscisic acid regulates root growth under osmotic stress conditions via an interacting hormonal network with cytokinin, ethylene and auxin.The New phytologist · 2016Article
- Ethylene and Hormonal Cross Talk in Vegetative Growth and Development.Plant physiology · 2015Review
- Spatiotemporal modelling of hormonal crosstalk explains the level and patterning of hormones and gene expression in Arabidopsis thaliana wild-type and mutant roots.The New phytologist · 2015Article
- Some fundamental aspects of modeling auxin patterning in the context of auxin-ethylene-cytokinin crosstalk.Plant signaling & behavior · 2015Article
- Endogenous Cytokinin Overproduction Modulates ROS Homeostasis and Decreases Salt Stress Resistance in Arabidopsis Thaliana.Frontiers in plant science · 2015Article
- Cloning and characterization of TaPP2AbB"-α, a member of the PP2A regulatory subunit in wheat.PloS one · 2014Article
- Hormonal crosstalk for root development: a combined experimental and modeling perspective.Frontiers in plant science · 2014Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Understanding how hormones and genes interact to coordinate plant growth is a major challenge in developmental biology. The activities of auxin, ethylene, and cytokinin depend on cellular context and exhibit either synergistic or antagonistic interactions. Here we use experimentation and network construction to elucidate the role of the interaction of the POLARIS peptide (PLS) and the auxin efflux carrier PIN proteins in the crosstalk of three hormones (auxin, ethylene, and cytokinin) in Arabidopsis root development. In ethylene hypersignaling mutants such as polaris (pls), we show experimentally that expression of both PIN1 and PIN2 significantly increases. This relationship is analyzed in the context of the crosstalk between auxin, ethylene, and cytokinin: in pls, endogenous auxin, ethylene and cytokinin concentration decreases, approximately remains unchanged and increases, respectively. Experimental data are integrated into a hormonal crosstalk network through combination with information in literature. Network construction reveals that the regulation of both PIN1 and PIN2 is predominantly via ethylene signaling. In addition, it is deduced that the relationship between cytokinin and PIN1 and PIN2 levels implies a regulatory role of cytokinin in addition to its regulation to auxin, ethylene, and PLS levels. We discuss how the network of hormones and genes coordinates plant growth by simultaneously regulating the activities of auxin, ethylene, and cytokinin signaling pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.