ReviewFrontiers in neural circuits2013
Regulation of zebrafish sleep and arousal states: current and prospective approaches.
Review in Frontiers in neural circuits, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 97 citations in OpenAlex.
- Disinhibition of cerebellar output by loss of restless legs syndrome-associated gene MEIS1.Current biology : CB · 2026Article
- Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish.Science advances · 2026Article
- Eye movement kinematics reveal novel circadian organization of sleep substates.Nature communications · 2026Article
- Zebrafish as a translational filter for natural sleep modulators.Frontiers in nutrition · 2026Review
- Contributions of Zebrafish to Our Understanding of the Function and Regulation of Sleep.Current sleep medicine reports · 2026Review
- Power calculations for larval zebrafish in light-dark transition test for developmental neurotoxicity.Neurotoxicology · 2026Article
- Harnessing Simple Animal Models to Decode Sleep Mysteries.Molecular biotechnology · 2025Review
- Quantifying the link between retinal performance and the optomotor response.Current biology : CB · 2025Article
- Sleeping upside-down: Knockdown of a sleep-associated gene induces daytime sleep in the jellyfishProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Postprandial Sleep in Short-Sleeping Mexican Cavefish.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2024Article
- Postprandial sleep in short-sleeping Mexican cavefish.bioRxiv : the preprint server for biology · 2024Article
- Analysis of sleep/wake cycles in zebrafish larvae.MethodsX · 2024Article
- Sleep and circadian rhythmicity as entangled processes serving homeostasis.Nature reviews. Neuroscience · 2024Review
- A new protocol for multispecies bacterial infections in zebrafish and their monitoring through automated image analysis.PloS one · 2024Article
- Context-dependent hyperactivity inFrontiers in molecular neuroscience · 2024Article
- Ontogenetic Plasticity in Shoaling Behavior in a Forage Fish under Warming.Integrative and comparative biology · 2023Article
- Article
- Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep.Science advances · 2023Article
- The Zebrafish, an Outstanding Model for Biomedical Research in the Field of Melatonin and Human Diseases.International journal of molecular sciences · 2022Review
- Larval Zebrafish as a Model for Mechanistic Discovery in Mental Health.Frontiers in molecular neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Every day, we shift among various states of sleep and arousal to meet the many demands of our bodies and environment. A central puzzle in neurobiology is how the brain controls these behavioral states, which are essential to an animal's well-being and survival. Mammalian models have predominated sleep and arousal research, although in the past decade, invertebrate models have made significant contributions to our understanding of the genetic underpinnings of behavioral states. More recently, the zebrafish has emerged as a promising model system for sleep and arousal research. Here we review experimental evidence that the zebrafish, a diurnal vertebrate, exhibits fundamental behavioral and neurochemical characteristics of mammalian sleep and arousal. We also propose how specific advantages of the zebrafish can be harnessed to advance the field. These include tractable genetics to identify and manipulate molecular and cellular regulators of behavioral states, optical transparency to facilitate in vivo observation of neural structure and function, and amenability to high-throughput drug screens to discover novel therapies for neurological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.