ArticleFrontiers in cellular neuroscience2013
Differential regulation of neurexin at glutamatergic and GABAergic synapses.
Article in Frontiers in cellular neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Prenatal maternal immune activation triggers lasting cell-specific transcriptomic dysregulation in the amygdala of primate offspring.Molecular psychiatry · 2026Article
- Janus Synapses as Modular Neurointerfaces.ACS applied materials & interfaces · 2026Review
- Social behavior in prepubertal neurexin 1α deficient rats: A model of neurodevelopmental disorders.Behavioral neuroscience · 2021Article
- Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells.Frontiers in molecular neuroscience · 2020Article
- SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function.PLoS biology · 2019Article
- Genetic insights and neurobiological implications from NRXN1 in neuropsychiatric disorders.Molecular psychiatry · 2019Review
- Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters.The Journal of cell biology · 2019Article
- Activity-dependent adaptations in inhibitory axons.Frontiers in cellular neuroscience · 2013Review
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7 authors.
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Abstract
Neurexins (Nrxs) have emerged as potential determinants of synaptic specificity, but little is known about their localization at central synapses. Here we show that Nrxs have a remarkably selective localization at distinct types of glutamatergic synapses and we reveal an unexpected ontogenetic regulation of Nrx expression at GABAergic synapses. Our data indicate that synapses are specified by molecular interactions that involve both Nrx-dependent and Nrx-independent mechanisms. We propose that differences in the spatio-temporal profile of Nrx expression may contribute to specify the molecular identity of synapses.
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