Evidence map›Paper›PMID 23576892›Full record

ArticleDialogues in clinical neuroscience2013

Applications of transcranial magnetic stimulation and magnetic seizure therapy in the study and treatment of disorders related to cerebral aging.

Bruce Luber, Shawn M McClintock, Sarah H Lisanby

Open access · diamondAbstract read
In one paragraph

Article in Dialogues in clinical neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Magnetic seizure therapy for people with schizophrenia.The Cochrane database of systematic reviews · 2023
    Pooled it
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Novel Therapeutic Approaches for Alzheimer's Disease: An Updated Review.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Article
  14. Brain Stimulation in Alzheimer's Disease.Frontiers in psychiatry · 2018
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Aging and neuroplasticity.Dialogues in clinical neuroscience · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bruce LuberDepartment of Psychiatry and Behavioral Sciences, Department of Psychology and Neuroscience, Duke University, Durham, NC, USA. bruce.luber@duke.edu
Shawn M McClintock
Sarah H Lisanby
Duke University · USThe University of Texas Southwestern Medical Center · US

Funding

Neural basis of cognitive reserve: fMRI/TMS studies of memory and agingK01AG031912 · NIA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI LUBER, BRUCE · 2008 to 2012
$652k
Translational Research Evaluating Neurocognitive Memory Processes (TREC-MP)K23MH087739 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI MCCLINTOCK, SHAWN M · 2010 to 2014
$641k
NIA NIH HHS K01 AG031912NIMH NIH HHS K23 MH087739
6 · The paper itself

Abstract

Transcranial magnetic stimulation (TMS) can be used to probe cortical function and treat neuropsychiatric illnesses. TMS has demonstrated neuroplastic effects akin to long-term potentiation and long-term depression, and therapeutic applications are in development for post-stroke recovery, Alzheimer's disease, and depression in seniors. Here, we discuss two new directions of TMS research relevant to cerebral aging and cognition. First, we introduce a paradigm for enhancing cognitive reserve, based on our research in sleep deprivation. Second, we discuss the use of magnetic seizure therapy (MST) to spare cognitive functions relative to conventional electroconvulsive therapy, and as a means of providing a more potent antidepressant treatment when subconvulsive TMS has shown modest efficacy in seniors. Whether in the enhancement of cognition as a treatment goal, or in the reduction of amnesia as a side effect, these approaches to the use of TMS and MST merit further exploration regarding their clinical potential.

Indexed as

AgingBrain DiseasesElectroconvulsive TherapySeizuresCerebral CortexCognitionHumansNeuronal PlasticityTranscranial Magnetic Stimulationagingmagnetic seizure therapyMSTneuroplasticityneuroscienceTMStranscranial magnetic stimulation

Identifiers

PMID23576892
PMCPMC3622472
OpenAlexW1682746507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.