ReviewDialogues in clinical neuroscience2013
Successful brain aging: plasticity, environmental enrichment, and lifestyle.
Review in Dialogues in clinical neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 5 syntheses or guidelines pooled it, 175 citations in OpenAlex.
- Overlooked cases of mild cognitive impairment: Implications to early Alzheimer's disease.Ageing research reviews · 2024Pooled it
- Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation.The Cochrane database of systematic reviews · 2022Pooled it
- The microbiota-gut- hippocampus axis.Frontiers in neuroscience · 2022Pooled it
- Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation.The Cochrane database of systematic reviews · 2014Pooled it
- Therapeutics with SPION-labeled stem cells for the main diseases related to brain aging: a systematic review.International journal of nanomedicine · 2014Pooled it
- Trial
- Trial
- Declines in motor transfer following upper extremity task-specific training in older adults.Experimental gerontology · 2019Trial
- Consciousness, subjectivity, and aging in western thought.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Article
- Comparison of the Efficacy of Different Exercise Modes on MCI Adults: A Network Meta-Analysis.Brain and behavior · 2025Review
- Age-related differences in resting glutamate levels and glutamate uptake in the hippocampus and frontal cortex of C57BL/6 mice.Neurobiology of aging · 2025Article
- Network Occlusion Sensitivity Analysis Identifies Regional Contributions to Brain Age Prediction.Human brain mapping · 2025Article
- Advanced Brain Age Prediction Using Multi-Head Self-Attention: A Comparative Analysis of Western and Middle Eastern MRI Datasets.Research square · 2025Article
- Exploring the landscape of physical activity and neuroplasticity research: a comprehensive bibliometric review.Frontiers in sports and active living · 2025Review
- Scaffolding theory of maturation, cognition, motor performance, and motor skill acquisition: a revised and comprehensive framework for understanding motor-cognitive interactions across the lifespan.Frontiers in human neuroscience · 2025Article
- Investigation of Metabolic and Inflammatory Disorder in the Aging FGF21 Knockout Mouse.Inflammation · 2024Article
- Mitigation of aging-related plasticity decline through taurine supplementation and environmental enrichment.Scientific reports · 2024Article
- Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Cognitive Reserve proxies can modulate motor and non-motor basal ganglia circuits in early Parkinson's Disease.Brain imaging and behavior · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is a physiological process that can develop without the appearance of concurrent diseases. However, very frequently, older people suffer from memory loss and an accelerated cognitive decline. Studies of the neurobiology of aging are beginning to decipher the mechanisms underlying not only the physiology of aging of the brain but also the mechanisms that make people more vulnerable to cognitive dysfunction and neurodegenerative diseases. Today we know that the aging brain retains a considerable functional plasticity, and that this plasticity is positively promoted by genes activated by different lifestyle factors. In this article some of these lifestyle factors and their mechanisms of action are reviewed, including environmental enrichment and the importance of food intake and some nutrients. Aerobic physical exercise and reduction of chronic stress are also briefly reviewed. It is proposed that lifestyle factors are powerful instruments to promote healthy and successful aging of the brain and delay the appearance of age-related cognitive deficits in elderly people.
Indexed as
Identifiers
23576888PMC3622468W1526640848What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.