ArticleHippocampus2013
Spatial scale and place field stability in a grid-to-place cell model of the dorsoventral axis of the hippocampus.
Article in Hippocampus, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Reproducible and predictable reorganization of place fields driven by grid subfield rate changes.bioRxiv : the preprint server for biology · 2026Article
- The role of prefrontal-hippocampal functional connectivity in schizophrenia-related cognitive dysfunction and the thalamic ventral midline involvement:Frontiers in neuroscience · 2025Review
- Differential involvement of the anterior and posterior hippocampus, parahippocampus, and retrosplenial cortex in making precise judgments of spatial distance and object size for remotely acquired memories of environments and objects.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Effects of social context manipulation on dorsal and ventral hippocampal neuronal responses.Hippocampus · 2023Article
- Place cells dynamically refine grid cell activities to reduce error accumulation during path integration in a continuous attractor model.Scientific reports · 2022Article
- Adapting hippocampus multi-scale place field distributions in cluttered environments optimizes spatial navigation and learning.Frontiers in computational neuroscience · 2022Article
- Dynamical self-organization and efficient representation of space by grid cells.Current opinion in neurobiology · 2021Review
- A computational grid-to-place-cell transformation model indicates a synaptic driver of place cell impairment in early-stage Alzheimer's Disease.PLoS computational biology · 2021Article
- A Model of Spatial Cell Development in Rat Hippocampus Based on Artificial Neural Network.Journal of healthcare engineering · 2021Article
- Reward anticipation selectively boosts encoding of gist for visual objects.Scientific reports · 2020Article
- Differences in reward biased spatial representations in the lateral septum and hippocampus.eLife · 2020Article
- Article
- Grid scale drives the scale and long-term stability of place maps.Nature neuroscience · 2018Article
- Dendritic GIRK Channels Gate the Integration Window, Plateau Potentials, and Induction of Synaptic Plasticity in Dorsal But Not Ventral CA1 Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Dorsoventral and Proximodistal Hippocampal Processing Account for the Influences of Sleep and Context on Memory (Re)consolidation: A Connectionist Model.Computational intelligence and neuroscience · 2017Article
- From grid cells to place cells with realistic field sizes.PloS one · 2017Article
- Megamap: flexible representation of a large space embedded with nonspatial information by a hippocampal attractor network.Journal of neurophysiology · 2016Article
- What do grid cells contribute to place cell firing?Trends in neurosciences · 2014Review
Corrections and comments
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Authors and funding
4 authors.
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Abstract
The rodent hippocampus and entorhinal cortex contain spatially modulated cells that serve as the basis for spatial coding. Both medial entorhinal grid cells and hippocampal place cells have been shown to encode spatial information across multiple spatial scales that increase along the dorsoventral axis of these structures. Place cells near the dorsal pole possess small, stable, and spatially selective firing fields, while ventral cells have larger, less stable, and less spatially selective firing fields. One possible explanation for these dorsoventral changes in place field properties is that they arise as a result of similar dorsoventral differences in the properties of the grid cell inputs to place cells. Here, we test the alternative hypothesis that dorsoventral place field differences are due to higher amounts of nonspatial inputs to ventral hippocampal cells. We use a computational model of the entorhinal-hippocampal network to assess the relative contributions of grid scale and nonspatial inputs in determining place field size and stability. In addition, we assess the consequences of grid node firing rate heterogeneity on place field stability. Our results suggest that dorsoventral differences in place cell properties can be better explained by changes in the amount of nonspatial inputs, rather than by changes in the scale of grid cell inputs, and that grid node heterogeneity may have important functional consequences. The observed gradient in field size may reflect a shift from processing primarily spatial information in the dorsal hippocampus to processing more nonspatial, contextual, and emotional information near the ventral hippocampus.
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