ArticleEuropean journal of epidemiology2013
Nutrient intake and nutrient patterns and risk of lung cancer among heavy smokers: results from the COSMOS screening study with annual low-dose CT.
Article in European journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- The association between dietary fiber intake and risk of lung cancer: a GRADE-assessed systematic review and dose response meta-analysis of prospective cohort studies.Nutrition journal · 2026Pooled it
- Adherence to Data-Driven Dietary Patterns and Lung Cancer Risk: A Systematic Review and Dose-Response Meta-Analysis.Nutrients · 2023Pooled it
- Dietary Patterns and Risk of Lung Cancer: A Systematic Review and Meta-Analyses of Observational Studies.Current nutrition reports · 2023Pooled it
- A Healthy Dietary Pattern Reduces Lung Cancer Risk: A Systematic Review and Meta-Analysis.Nutrients · 2016Pooled it
- Nutrient patterns and mortality: results from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study.Nutrition journal · 2025Article
- Association between empirically derived nutrient patterns and breast cancer: a case-control study in a Middle Eastern country.BMC nutrition · 2024Article
- Etiology of lung cancer: Evidence from epidemiologic studies.Journal of the National Cancer Center · 2022Review
- Nutrient patterns and their relation to obesity and metabolic syndrome in Iranian overweight and obese adult women.Eating and weight disorders : EWD · 2022Article
- Possible Biochemical Processes Underlying the Positive Health Effects of Plant-Based Diets-A Narrative Review.Nutrients · 2021Review
- Indices of Diet Quality and Risk of Lung Cancer in the Women's Health Initiative Observational Study.The Journal of nutrition · 2021Observational
- Association of Nutrient Patterns and Their Relation with Obesity in Iranian Adults: a Population Based Study.Clinical nutrition research · 2021Article
- Article
- Nutrient patterns and cardiometabolic risk factors among Iranian adults: Tehran lipid and glucose study.BMC public health · 2020Article
- Association of Dietary Fiber and Yogurt Consumption With Lung Cancer Risk: A Pooled Analysis.JAMA oncology · 2020Article
- Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China.BMC cancer · 2018Article
- Different dietary patterns and reduction of lung cancer risk: A large case-control study in the U.S.Scientific reports · 2016Article
- Dietary inflammatory index and risk of lung cancer and other respiratory conditions among heavy smokers in the COSMOS screening study.European journal of nutrition · 2016Article
- Nutrient patterns and their relation to general and abdominal obesity in Iranian adults: findings from the SEPAHAN study.European journal of nutrition · 2016Article
- Index-based dietary patterns and risk of lung cancer in the NIH-AARP diet and health study.European journal of clinical nutrition · 2016Article
- Total antioxidant status in lung cancer is associated with levels of endogenous antioxidants and disease stage rather than lifestyle factors - preliminary study.Contemporary oncology (Poznan, Poland) · 2016Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of nutrients in lung cancer aetiology remains controversial and has never been evaluated in the context of screening. Our aim was to investigate the role of single nutrients and nutrient patterns in the aetiology of lung cancer in heavy smokers. Asymptomatic heavy smokers (≥20 pack-years) were invited to undergo annual low-dose computed tomography. We assessed diet using a self-administered food frequency questionnaire and collected information on multivitamin supplement use. We performed principal component analysis identifying four nutrient patterns and used Cox proportional Hazards regression to assess the association between nutrients and nutrients patterns and lung cancer risk. During a mean follow-up of 5.7 years, 178 of 4,336 participants were diagnosed with lung cancer by screening. We found a significant risk reduction of lung cancer with increasing vegetable fat consumption (HR for highest vs. lowest quartile = 0.50, 95% CI = 0.31-0.80; P-trend = 0.02). Participants classified in the high "vitamins and fiber" pattern score had a significant risk reduction of lung cancer (HR = 0.57; 95% CI = 0.36-0.90, P-trend = 0.01). Among heavy smokers enrolled in a screening trial, high vegetable fat intake and adherence to the "vitamin and fiber" nutrient pattern were associated with reduced lung cancer incidence.
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