ArticleInternational urology and nephrology2013
Increased night heart rate is associated with worse large artery elasticity in chronic kidney disease patients.
Article in International urology and nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 6 citations in OpenAlex.
- Non-dipping pulse rate and chronic changes of the kidney in patients with chronic kidney disease.Frontiers in cardiovascular medicine · 2023Article
- Article
- Nondipping heart rate and associated factors in patients with chronic kidney disease.Clinical and experimental nephrology · 2019Article
- Serum endocan and circadian heart rate variability in non-dialysis stage 5 chronic kidney disease patients.International urology and nephrology · 2018Article
- Autonomic Dysfunction: How to Identify and When to Treat?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2016Review
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7 authors at 5 institutions in 2 countries.
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Abstract
backgroundChronic kidney disease (CKD) is associated with high overall and cardiovascular mortality. Numerous studies have reported that increased heart rate is a risk factor for all-cause mortality. We investigated the link between sleep heart rate and artery stiffness in CKD patients.
methodsIn a cross-sectional study, we enrolled 100 prevalent Chinese CKD patients (55 males, aged 52.5 ± 16.40 years). Heart rate was measured with an automatic system. Arterial stiffness was evaluated by using a calibrated tonometer.
resultsLarge artery elasticity index (LAEI) was positively correlated with body mass index and hemoglobin but negatively associated with age and systolic blood pressure. Furthermore, LAEI was negatively associated with glomerular filtration rate (GFR) and sleep heart rate. In multivariate regression, LAEI was independently predicted by SBP, BMI, age, sleep heart rate, and gender. Adjusted R (2) of the model was 0.486.
conclusionElevated sleep heart rate is significantly associated with increased arterial stiffness in CKD patients. Further investigation is needed to explore the potential benefits of sleep heart rate lowering therapy in this patient group.
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