ArticleDalton transactions (Cambridge, England : 2003)2013
A europium(III)-based PARACEST agent for sensing singlet oxygen by MRI.
Article in Dalton transactions (Cambridge, England : 2003), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Lanthanide Complexes (GdChemistry, an Asian journal · 2022Article
- Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers.Chemical reviews · 2019Review
- Nitroxyl Modified Tobacco Mosaic Virus as a Metal-Free High-Relaxivity MRI and EPR Active Superoxide Sensor.Molecular pharmaceutics · 2018Article
- Spectroscopic Characterization of the 3+ and 2+ Oxidation States of Europium in a Macrocyclic Tetraglycinate Complex.Inorganic chemistry · 2016Article
- Recent Advances on Luminescent Enhancement-Based Porous Silicon Biosensors.Pharmaceutical research · 2016Review
- Background-free in-vivo Imaging of Vitamin C using Time-gateable Responsive Probe.Scientific reports · 2015Article
- The elements of life and medicines.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2015Article
- Overcoming the concentration-dependence of responsive probes for magnetic resonance imaging.Metallomics : integrated biometal science · 2015Review
- Double agents and secret agents: the emerging fields of exogenous chemical exchange saturation transfer and TResearch and reports in nuclear medicine · 2015Article
- Oxidation-responsive Eu(2+/3+)-liposomal contrast agent for dual-mode magnetic resonance imaging.Chemical communications (Cambridge, England) · 2014Article
- Redox- and hypoxia-responsive MRI contrast agents.ChemMedChem · 2014Review
- Lanthanide probes for bioresponsive imaging.Chemical reviews · 2014Review
- Comparison of divalent transition metal ion paraCEST MRI contrast agents.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014Review
- A review of responsive MRI contrast agents: 2005-2014.Contrast media & molecular imagingReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
A europium(III) DOTA-tetraamide complex was designed as a MRI sensor of singlet oxygen ((1)O2). The water soluble, thermodynamically stable complex reacts rapidly with (1)O2 to form an endoperoxide derivative that results in an ∼3 ppm shift in the position of the Eu(III)-bound water chemical exchange saturation transfer (CEST) peak. The potential of using this probe to detect accumulation of the endoperoxide derivative in biological media by ratiometric CEST imaging was demonstrated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.